The purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (EC) as a carrier polymer through an emulsion solvent evaporation method. These evaluations characterized the pattern of drug release from prepared microspheres. Nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. The effect of proces...

OBJECTIVES The aim of this study was to improve flowability and compressibility characteristics of starch to use as a suitable excipient in direct compression tabletting. Quasi-emulsion solvent diffusion was used as a crystal modification method. MATERIALS AND METHODS Corn starch was dissolved in hydrochloric acid at 80°C and then ethanol as a non-solvent was added with lowering temperature u...

The objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (MA) using two polymers with different characteristics as ethylcellulose (EC) and/or cellulose acetate phthalate (CAP). Microspheres were prepared by the modified emulsion solvent evaporation (MESE). The effect of drug-polymer interaction was studied for each of microspheres. Important param...

In this study, we prepared all-trans retinoic acid (ATRA)-encapsulated, surfactant-free, PLGA nanoparticles. The nanoparticles were formed by nanoprecipitation process, after which the solvent was removed by solvent evaporation or dialysis method. When a nanoparticle was prepared by the nanoprecipitation solvent evaporation method, the nanoparticles were bigger than the nanoparticles of the nan...

In this study, Analytical Hierarchy Process (AHP) was employed to select the best method for the preparation of Nateglinide (NTG)loaded nanoparticles. There are various techniques available for the development of nanoparticles like Nanoprecipitation or Solvent displacement, Ionic gelation, Solvent evaporation method etc. and choosing the best method is a crucial one. AHP is one of the widely us...

Microspheres formulated from poly (D, L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release properties of the PLGA microspheres were evaluated. Simvastatin (SIM)-loaded PLGA microspheres were prepared by oil-in-water emulsion/solvent evaporation method. The microspheres...

The development of porous films with an accessible high specific surface area is important for designing new adsorbents, sensors, or catalyst supports. Here, we describe a simple method to prepare silica foam coating using calcium chloride-assisted evaporation-induced emulsification method. An alcoholic sol containing chloride and poly(ethylene oxide)-based polymer deposited on substrate by dip...

A novel method for the fabrication of monodisperse mesoporous silica particles is suggested. It is based on the formation of well-defined equally sized emulsion droplets using a microfluidic approach. The droplets contain the silica precursor/surfactant solution and are suspended in hexadecane as the continuous oil phase. The solvent is then expelled from the droplets, leading to concentration ...

In this work, different sizing agent aqueous dispersions based on polyetherimide (PEI) were elaborated in order to improve the interface between carbon fibers and a thermoplastic matrix (PEEK). The dispersions were obtained by the emulsion/solvent evaporation technique. To optimize the stability and the film formation on the fibers, two surfactants were tested at different concentrations, with ...