Background: Cancer of the endometrium is the most common gynecologic malignancy in western and industrial countries, and is the second most common in developing countries, therefore it is of special importance. Adenocarcinoma of the endometrium is the most common type of uterine cancer. The prevalence of endometrial cancer in young women under the age of 40 in western country is very low and ab...

Data are limited regarding the occurrence of endometrial cancer after endometrial ablation (EA). A systematic review of the English-language medical literature was performed of cases of endometrial cancer after EA. This review included the present case report involving a 47-year-old woman with a diagnosis of stage IA, grade 1 endometrial adenocarcinoma 5 years after radiofrequency EA. The syste...

abstracthydatid disease is a widespread parasitic infection caused by tapewormechinococcus and it affects mainly the liver, but other organs such as pelvic organscould be involved very rare. here we report a case of hydatid cyst with involvementof oviduct in a woman with endometrial cancer. it was misdiagnosed as a multicysticright ovarian mass before surgery and by microscopic study it was sho...

objective: the purpose of this pilot study was to determine whether the mri and biomarkers human epididymis protein 4 (he 4 ) and ca 125 correlate with depth of myometrial invasion, histologic grade, cervical involvement and nodal metastases in patients with endometrioid adenocarcinoma of the uterus. materials and methods: this was a prospective, observational study in women with biopsy-proven ...

endometrial adenocarcinoma is uncommon in fewer than 40-year-old people. the first common sign and symptoms are abnormal vaginal bleeding and discharge. metastasis is occurred in the late stage. here we present a 31-year-old nullipar woman who was admitted to surgical ward with enlarged right inguinal lymphnode from one month ago. she had no history of previous malignancy, infectious condition,...

background: there are some controversial data on application of progesterone and progesterone plus estrogen at luteal phase. objective: to investigate the effects of different luteal support hormones on the alkaline phosphates (alp) activity in the endometrial epithelium and endometrial thickness during superovulation process for obtaining the optimized endometrial receptivity in animal model. ...

In order to study changes occurring on the surfaces of human endometrial epithelial cells in the presence of an implanted blastocyst, we used scanning electron microscopy for investigation of five endometrial biopsies and three human implantation sites obtained in vitro. All specimens showed areas with endometrial pinopodes, separated by cells displaying microvilli or cilia at the apical surfac...

This report describes a uterine tumour exhibiting areas of both endometrial stromal and smooth muscle diVerentiation. There was extensive intravasular permeation within the myometrium as well as extrauterine vascular involvement. The endometrial stromal component had a myxoid appearance and the smooth muscle component exhibited the typical features of intravenous leiomyomatosis. An additional f...

OBJECTIVE To evaluate the role of transvaginal power Doppler sonography to discriminate between benign and malignant endometrial conditions in women presenting with postmenopausal bleeding and thickened endometrium at baseline sonography. METHODS Ninety-one postmenopausal women (median age, 58 years; range, 47-83 years) presenting with uterine bleeding and a thickened endometrium (> or = 5-mm...

Purpose: Effective treatments for advanced endometrial cancer are lacking. Novel therapies that target specific pathways hold promise for better treatment outcomes with less toxicity. Mutation activation of the FGFR2/ RAS/ERK pathway is important in endometrial tumorigenesis. RPS6KA6 (RSK4) is a putative tumor suppressor gene and is a target of the ERK signaling pathway. We explored the role of...