Eosinophilic pustular folliculitis or Ofuji's disease is a non-infectious eosinophilic infiltration of hair follicles, which usually presents with itchy papules and pustules in a circinate configuration. We report this case of an immunocompetent patient with erythematous papules and plaques without macropustules diagnosed as eosinophilic pustular folliculitis-a rarely reported entity outside Ja...

Graft-versus-host disease (GVHD) is a severe and frequent complication of allogeneic bone marrow transplantation (BMT) that involves the gastrointestinal (GI) tract and lungs. The pathobiology of GVHD is complex and involves immune cell recognition of host Ags as foreign. We hypothesize a central role for the collectin surfactant protein A (SP-A) in regulating the development of GVHD after allo...

Gastrointestinal (GI) stromal tumors are mesenchymal tumors that arise from the GI tract. In rare cases, these tumors are found in intra-abdominal sites unrelated to the GI tract and are immunohistochemically similar to their GI tract counterparts. Primary pancreatic GI stromal tumors are very rare, with only 4 previous cases reported.

In some patients, eosinophilic gastroenteritis(EG) occurs in those with food allergy. We experienced a non-atopic asthmatic who had an EG associated with food allergy to fish and eggs, and blood eosinophilia. A skin prick test and RAST to causative food allergens showed a negative result. A fiber-optic endoscopic biopsy from the gastric mucosa showed an intense eosinophilic infiltration. We cou...

There are two lesions which are often confused despite their quite distinct clinical and pathological differences: the inflammatory fibroid polyp and eosinophilic gastroenteritis. Other eosinophilic lesions likely to be encountered in the gut also pose problems of differential diagnosis.

The endoderm germ layer contributes to the respiratory and gastrointestinal (GI) lineages during development, giving rise to an array of specialized epithelial cell types lining organs, including the thyroid, thymus, lungs, liver, biliary system, pancreas, and intestines. This SnapShot timelines and summarizes key stages following gastrulation, including endoderm patterning, organ specification...

The fatal outcome in the case described was unfortunate but was undoubtedly largely attributable to the patient's respiratory condition. The great difficulty which may be encountered in closing the duodenal stump in the presence of massive infiltration must, however, be stressed. We are indebted to Dr. A. A. Miller for valuable assistance with the pathological studies and for helpful advice. RE...

The fatal outcome in the case described was unfortunate but was undoubtedly largely attributable to the patient's respiratory condition. The great difficulty which may be encountered in closing the duodenal stump in the presence of massive infiltration must, however, be stressed. We are indebted to Dr. A. A. Miller for valuable assistance with the pathological studies and for helpful advice. RE...

Abstract Histopathologic analysis of biopsy specimens obtained via white light endoscopy (WLE) is the gold standard for diagnosis several mucosal diseases in upper gastrointestinal (GI) tract. However, this care entails a series critical shortcomings such as missing depth information, high costs, time inefficiency, low-resolution imaging vivo , sampling variability, intrinsic tissue-specific co...

Eosinophilic gastroenteritis is a rare condition of unknown etiology characterized by eosinophilic infiltration of the bowel. Corticosteroids are the mainstay of EG therapy. Although rare, steroid-resistant EG could be a life-threatening condition with tissue destructive evolution. Associations of eosinophilic gastroenteritis with systemic lupus erythematosus have rarely been reported. In this ...