abstract objective: abnormal values of the transient ischemic dilation (tid) ratio are associated with severe and extensive coronary artery disease (cad). tid can be used as a diagnostic and prognostic marker of cad in diabetic patients. the aim of current study was to determine the pooled estimate of tid ratio in single myocardial perfusion scan in diabetic patients by a systematic review and ...

  Objective(s): Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary artery disease (CAD) risk. The aim of this study was to study the association of the Apolipoprotein E genotypes with coronary artery disease in the Iranian population.   Materials and Methods: The Apolipoprotein E genotype in DNA samples extracted from 66 CAD+ patients and 61 control s...

Twins have fascinated human communities since the beginning of recorded history. In cardiovascular research, twin studies played a pivotal role in the discovery of the genetic basis of coronary artery disease, myocardial infarction and most of their associated risk factors. Matched for age, prenatal and postnatal environmental factors, discordant monozygous twin pairs provide a means to enhance...

Platelets have been implicated and abnormal platelet function proposed in the pathogenesis of coronary artery disease (CAD). This investigation examines platelet function in men with stable, arteriographically defined CAD and correlates results with lipid pattern, history of angina or 'myocardial infarction and smoking habits. Platelet survival (51Chromium method), adhesiveness, and aggregation...

conclusions in total, application of therapeutic approaches in patients with cad depends on many factors. in our study not only risk factors such as gender, lifestyle, smoking, alcohol abuse, diabetes and hypertension were associated with the incidence of cad, but also they were highly correlated with the severity of the disease. results the mean age of total patients was 58.3 ± 11.5 years (p =...

background one of the most important causes of mortality in developed and developing countries is coronary artery disease. coronary artery disease (cad) may develop by deposition of lipid, fibrous or calcified debris on the surface of the coronary artery lumen. fibrous plaque and calcified plaque may cause substantial stenosis of coronary arteries leading to ischemia of heart muscle while lipid...

Celiac disease (CD) is an immune-mediated enteropathy involving the small intestines. Genetic and environmental risk factors as well as autoimmunity have been linked to its etiology. Studies have shown that coronary artery disease, autoimmune myocarditis, arrhythmias and premature atherosclerosis are more prevalent in individuals with CD compared to individuals without the disease. In this case...

Epidemiological research over the last 50 years has discovered a plethora of biomarkers (including molecules, traits or other diseases) that associate with coronary artery disease (CAD) risk. Even the strongest association detected in such observational research precludes drawing conclusions about the causality underlying the relationship between biomarker and disease. Mendelian randomization (...

conclusions the eft, as measured by echocardiography, with a cut off value 2.95 mm has a strong association with premature cad. results among baseline characteristics, waist circumference, triglyceride levels, cigarette smoking and history of statin use were significantly higher in the cad group. the body mass index (bmi) was significantly higher in the non-cad group. according to echocardiogra...