IN a large proportion of cases of tuberculosis of the urinary and genital system the sequence of events is as follows :-First the kidney is affected, then the ureter and bladder; later the vesicula, prostate, vas deferens, epididymis, and testis may be involved in the male subject. In the great majority of cases the bladder symptoms predominate, so that the case is often sent to the surgeon wit...

The epididymis is the site where spermatozoa are matured and stored. After orchidectomy, this tissue loses up to 80% of its weight. In the prostate, androgen withdrawal by orchidectomy is associated with apoptotic cell death. The objective of the present study was to investigate whether apoptotic cell death is involved in the androgen-dependent weight loss found in the rat epididymis after orch...

The enzyme steroid 5 alpha-reductase (EC 1.3.1.22) catalyzes the conversion of testosterone to its more potent form, dihydrotestosterone (DHT), in many androgen-sensitive target tissues. In the epididymis, the 5 alpha-reduced metabolites of testosterone, DHT and 5 alpha-androstan-3 alpha, 17 beta-diol (3 alpha-diol), are considered the primary regulators of epididymal structure and function. Tw...