epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. here a case of 58-year-old female presented with left cheek swelling of one-year duration. ct scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. histological examin...

In this contribution, we review the molecular and physiological barriers to oral delivery of peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro systems with special emphasis on human intestine in Ussing chambers. First, the molecular constraints to peptide absorption are discussed. Then the physiological barriers to peptide delivery are examined. These...

radiography is one of the most valuable diagnostic tools used in comprehensive dental care. although there is no safe level of radiation exposure, the possible risk associated with exposure to radiation, must be elucidated. to date, a variety of assays have been proposed to assess the mutagenic potential of genotoxicants; however, these methods are typically laborious and time consuming. the ai...

Abstract Over the past decade, T cell immunotherapy has changed face of cancer treatment, providing robust treatment options for several previously intractable cancers. Unfortunately, many epithelial tumors with high mortality rates respond poorly to immunotherapy, and an understanding key impediments is urgently required. Cancer-associated fibroblasts (CAFs) comprise most frequent nonneoplasti...

There is increasing evidence that surface curvature at a near-cell-scale influences cell behaviour. Epithelial or endothelial cells lining small acinar tubular body lumens, as those of the alveoli blood vessels, experience such highly curved surfaces. In contrast, most commonly used culture substrates for in vitro modelling these human tissue barriers, ion track-etched membranes, offer only fla...

The goal of the PRIN2005 “EAH conservation KM system” research project, funded by Italian Ministry of Research, is to establish an advanced integrated approach to conservation of Earthen Architecture Heritage (EAH) that support main design and planning of conservation actions, reducing the technical risk through suitable and compatible measures. Knowledge Management for supporting EAH conservat...

stem cells located at the limbus ,  are the ultimate source for regeneration of the corneal epithelium in the normal and traumatized states.  when limbal stem cells are dysfunctional or deficient, limbal stem cell deficiency (lscd) develops. its surgical management depends on laterality and severity of corneal-limbal involvement. conventional methods of stem cell transplantation are conjunctiva...