Chronic ovulation as a contributing factor for the development of epithelial ovarian cancer in women has long been an outstanding hypothesis. To test the incessant ovulation hypothesis, mice were superovulated using weekly ip injections of pregnant mare serum gonadotropin (5 IU/animal), followed 48 h later by human chorionic gonadotropin (5 IU/animal). Wild-type CD1 mice were used along with CD...

background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

background: magnetized water has made many improvements in industry, agriculture and medicine. however its utilization in medicine still remains controversial. objective:  in this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice. materials and methods:  e...

background: despite the extensive information available in the literature, cell surface marker signature of human amniotic epithelial cells (haecs) remains controversial. the aim of the present study was to characterize immuno-phenotypic features, proliferative capacity and immunogenicity of haecs. we also tested whether expression of some cell surface markers is influenced by the type of tryps...

one of the methods to enhance bio-accessibility of drugs like acridone and its oxime is toform inclusion complexes with β-cyclodextrin. the formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. the aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. the studyof thermodynamic parameters like δg,...

Conjunctival biopsy was performed in two siblings with adult-form galactosialidosis. Electron microscopically, several types of intracytoplasmic inclusion were observed in the fibroblasts in conjunctival stroma, lymphatic capillary endothelial cells, Schwann cells, and epithelial cells. Membrane-bound vesicles with fibrillogranular content were frequently observed, and occasional lamellar struc...

Ophthalmic examination yielded the following results: vision: OD: 20/40, OS: 20/40; intraocular pressure (IOP): OD: 15 mm Hg, OS: 15 mm Hg. Eye position and motion were normal. Slit lamp examination showed a purple-hued cystic mass nasally of the left eye, extending to the orbit with clear verge and slight congestion (Figure 1). Orbital magnetic resonance imaging (MRI) revealed a mass in front ...

introduction epithelial rejection typically begins in a linear pattern from the periphery of the graft and progresses centripetally. here in, we reported a patient with a new presentation of corneal epithelial graft rejection. case presentation a 23-year-old man presented with blurred vision two months after penetrating keratoplasty. conclusions slit lamp examination revealed sharply demarcated...