OBJECTIVE To evaluate corneal scar formation and new collagen deposition after laser subepithelial keratomileusis (LASEK) compared with photorefractive keratectomy (PRK) in the leghorn chick corneal model. METHODS Leghorn chick corneas treated with LASEK surgery (using 20% ethanol for 30 seconds) or PRK were evaluated by indirect confocal immunofluorescence and transmission electron microscop...

PURPOSE To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopia ranged from 3.25 to 7.00 diopters (D). Uncorrected and corrected visual ac...

PURPOSE To evaluate the efficacy of unilateral photorefractive keratectomy to correct anisometropia induced by retinal detachment surgery. METHODS Photorefractive keratectomy was performed in 10 eyes of 10 patients with anisometropia induced by previous retinal detachment surgery. The Aesculap Meditec MEL 60 excimer laser was used. RESULTS Preoperative mean spherical equivalent refraction w...

BACKGROUND We report a patient with Salzmann's nodular degeneration in whom the disease occurred without a history of keratitis and recurred twice after keratectomy. CASE A unilateral case of symptomatic Salzmann's nodular degeneration developed after cataract surgery in a 75-year-old woman. OBSERVATIONS We performed superficial keratectomy and amniotic membrane transplantation two times, b...

PURPOSE To evaluate the long-term side effects of mitomycin C (MMC) assisted photorefractive keratectomy (PRK) on corneal keratocytes of highly myopic eyes. METHODS Twenty-eight patients with bilateral myopia from -7.00 to -14.25 diopters (D) underwent PRK on both eyes, one eye of each patient received topical application of 0.02% MMC for 2 minutes immediately after the PRK procedure. Corneal...

BACKGROUND The purpose of this study was to compare differences in visual outcomes, higher-order aberrations, contrast sensitivity, and dry eye in patients undergoing photorefractive keratectomy using wavefront-guided VISX CustomVue™ and wavefront-optimized WaveLight(®) Allegretto platforms. METHODS In this randomized, prospective, single-masked, fellow-eye study, photorefractive keratectomy ...

BACKGROUND We conducted a clinical trial to evaluate the efficacy and safety of excimer laser photorefractive keratectomy (PRK) and photoastigmatic refractive keratectomy (PARK) using the Nidek EC-5000 excimer laser. METHODS A total of 67 eyes from 47 patients whose average age was 35 years were enrolled in the study. The mean spherical equivalent of the manifest refraction before surgery was...

BACKGROUND Silicon hydrogel bandage contact lenses are used to enhance epithelial healing, control surface-generated pain, and prevent epithelial erosions after refractive surgery. Considering the importance of faster reepithelialization in preventing complications of photorefractive keratectomy (PRK) and the fact that the features and specifications of these commercially-available lenses are d...

PURPOSE To compare the efficacy of 2 types of silicone hydrogel bandage contact lenses with high oxygen transmissibility after photorefractive keratectomy (PRK). SETTING Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece. METHODS In this prospective study, 1 eye of patients having bilateral PRK was randomly fitted with a bandage contact lens o...