نتایج جستجو برای: es models

تعداد نتایج: 981598  

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Pedro J Beltran Young-Ah Chung Gordon Moody Petia Mitchell Elaina Cajulis Steven Vonderfecht Richard Kendall Robert Radinsky Frank J Calzone

Ewing's and osteogenic sarcoma are two of the leading causes of cancer deaths in children and adolescents. Recent data suggest that sarcomas may depend on the insulin-like growth factor type 1 (IGF-1) receptor (IGF1R) and/or the insulin receptor (INSR) to drive tumor growth, survival, and resistance to mammalian target of rapamycin complex 1 (mTORC1) inhibitors. We evaluated the therapeutic val...

Journal: :Spektrum der Augenheilkunde 2005

2006
Jan Recker Jan Mendling Wil M. P. van der Aalst Michael Rosemann

Enterprise Systems potentially lead to significant efficiency gains but require a well-conducted configuration process. A promising idea to manage and simplify the configuration process is based on the premise of using reference models for this task. Our paper continues along this idea and delivers a two-fold contribution: first, we present a generic process for the task of model-driven Enterpr...

Journal: :journal of linear and topological algebra (jlta) 0
d ebrahimi baghaa department of mathematics, faculty of science, islamic azad university, centeral tehran branch, p. o. box 13185/768, tehran, iran.

let a be a banach algebra and e be a banach a-bimodule then s = a  e, the l1-direct sum of a and e becomes a module extension banach algebra when equipped with the algebras product (a; x):(a′; x′) = (aa′; a:x′ + x:a′). in this paper, we investigate △-amenability for these banach algebras and we show that for discrete inverse semigroup s with the set of idempotents es, the module extension bana...

2012
Çetin KURNAZ Hülya GÖKALP

This paper demonstrates a novel approach to determining the optimum guard interval for a multicarrier code division multiple access (MC-CDMA) system. Analytical expressions for useful and interference power are derived as a basis for comparison. From these, an expression for the signal-to-noise ratio of a detected bit is derived and used to determine the optimum guard interval for a given chann...

2015
June Stevens Fang-Shu Ou Kimberly P. Truesdale Donglin Zeng Amber E. Vaughn Charlotte Pratt Dianne S. Ward

BACKGROUND Parent-reported 24-h diet recalls are an accepted method of estimating intake in young children. However, many children eat while at childcare making accurate proxy reports by parents difficult. OBJECTIVE The goal of this study was to demonstrate a method to impute missing weekday lunch and daytime snack nutrient data for daycare children and to explore the concurrent predictive an...

2015
José Luis Ordóñez Ana Teresa Amaral Angel M. Carcaboso David Herrero-Martín María del Carmen García-Macías Vicky Sevillano Diego Alonso Guillem Pascual-Pasto Laura San-Segundo Monica Vila-Ubach Telmo Rodrigues Susana Fraile Cristina Teodosio Agustín Mayo-Iscar Miguel Aracil Carlos María Galmarini Oscar M. Tirado Jaume Mora Enrique de Álava

Recent preclinical evidence has suggested that Ewing Sarcoma (ES) bearing EWSR1-ETS fusions could be particularly sensitive to PARP inhibitors (PARPinh) in combination with DNA damage repair (DDR) agents. Trabectedin is an antitumoral agent that modulates EWSR1-FLI1 transcriptional functions, causing DNA damage. Interestingly, PARP1 is also a transcriptional regulator of EWSR1-FLI1, and PARPinh...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم انسانی 1389

rivers and runoff have always been of interest to human beings. in order to make use of the proper water resources, human societies, industrial and agricultural centers, etc. have usually been established near rivers. as the time goes on, these societies developed, and therefore water resources were extracted more and more. consequently, conditions of water quality of the rivers experienced rap...

2006
Bo Li

We consider a class of continuum models of epitaxial growth of thin films with two competing mechanisms: (1) the surface relaxation described by high-order gradients of the surface profile; and (2) the Ehrlich-Schwoebel (ES) effect which is the asymmetry in the adatom attachment and detachment to and from atomic steps. Mathematically, these models are gradient-flows of some effective free-energ...

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