Pseudomonas aeruginosa, a Gram-negative bacterium that causes severe hospital-acquired infections, is grouped as an ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogen because of its extensive drug resistance phenotypes and effects on human health worldwide. Five multidrug resistant P. ae...

In the course of conducting forensic analysis of human skeletal material, anthropologists are exposed to a number of biological and chemical hazards. This paper reviews the primary concerns in terms of infection or exposure. Handling of human tissue provides an avenue through which bloodborne pathogens may be transported. Scene recovery also includes a set of hazards through exposure to human, ...

Antibiotic resistance is one of the world’s most urgent public health threats. According to Centers for Disease Control and Prevention, at least 2.8 million people get an antibiotic-resistant infection each year, more than 35,000 die in United States from these infections. The development new antibiotics essential combat this crisis prevent loss additional lives. Natural products have historica...

BACKGROUND Comparing published trial patients and non-trial patients in clinical practice, clinicians often doubt whether critically ill patients are sufficiently represented in randomised clinical trials. PATIENTS AND METHODS This study evaluated the extent of infection with multidrug-resistant (MDR) pathogens, anti-microbial combination therapy, off-label use and targeted-treatment in trial...