Abstract Background Sclerotium rolfsii is a potent producer of many secondary metabolites, one which like scleroglucan an exopolysaccharide (EPS) appreciated as multipurpose compound applicable in industrial fields. Results Aspartate transaminase ( AAT1 ) catalyzes the interconversion aspartate and α-ketoglutarate to glutamate oxaloacetate. We selected oxalate metabolic pathway target CRISPR/Ca...

Apples (Malus × domestica Borkh.) can be categorized into early-, medium-, and late-ripening cultivars based on the length of fruit developmental phases. The lengthening apple ripening period has a direct impact its economic worth market competitiveness, although underlying mechanism is mostly unclear. In current study, development maturation early-ripening ‘Geneva Early’ (GE) ‘Hanfu’ (HF) were...

Elicitors could be used as the enhancer of plant secondary-metabolite synthesis and could play an important role in biosynthetic pathways of important medicinal compounds. The present study investigated the effect of abiotic elicitor (fungal extract of Fusarium graminearum) and two abiotic elicitors (methyl jasmonate and salicylic acid) at different concentrations in 18- and 30-day-old cultures...

In continuation of our search for new bioactive compounds from soil microbes, a fluorescent Pseudomonas strain isolated from paddy field soil of Kuttanad, Kerala, India was screened for the production of bioactive secondary metabolites. This strain was identified as Pseudomonas mosselii through 16S rDNA gene sequencing followed by BLAST analysis and the bioactive metabolites produced were purif...

The hallmark trait of fungal secondary-metabolite gene clusters is well established, consisting of contiguous enzymatic and often regulatory gene(s) devoted to the production of a metabolite of a specific chemical class. Unexpectedly, we have found a deviation from this motif in a subtelomeric region of Aspergillus fumigatus. This region, under the control of the master regulator of secondary m...