Objective: To describe the safety of medicines available in “Brazilian List Essential Medicines” (RENAME/2022) for main comorbidities that affect older persons according to Beers criteria 2019. Methods: Medicines listed RENAME and recommended by respective Brazilian medical guidelines treatment hypertension, heart failure, diabetes, neurological/ psychiatric diseases were evaluated their profil...

Objectives: The study aims at evaluating the validity of national list essential medicines (NLEM) 2015 for affecting blood in 2022. essentially conducting a cost analysis that mainly compares variation between highest and lowest priced branded variants same. Material Methods: takes into account aforementioned two classes “Medicines Affecting Blood,” which is 10.1–antianemia 10.2–medicines coagu...

OBJECTIVE To review the use of evidence in the market approval process, reimbursement, and price control mechanisms for medicines and medical devices in Thailand, South Korea, and Taiwan. METHODS Documentary reviews supplemented by interviews with senior policymakers of relevant public health authorities. RESULTS Drug regulatory authorities play a vital role in the market authorization proc...

OBJECTIVE To analyze the profile of claimants and medicines demanded in lawsuits. METHODS Descriptive study that examined 827 lawsuits with 1,777 demands of access to medicines in the period between July 2005 and June 2006 in the state of Minas Gerais, Southeastern Brazil. There were examined the type of health care provided to claimants and their attorneyship. The medicines were described ba...

It is difficult to draw up a list of medicines that are essential for infants and children. It is clear, however, that many of the medicines used appropriately to treat infants and children are not licensed for such use.1 The medicines concerned may be used outside the terms of their product license, ie, used off-label, or unlicensed for use in children at any age.2 Off-label use appears to be ...

OBJECTIVE To evaluate indicators related to the rational use of medicines and its associated factors in Basic Health Units. METHOD This is a cross-sectional study carried out in a representative sample of Brazilian cities included in the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços, 2015 (PNAUM - National Survey on Access, Use and Promotion ...

OBJECTIVES To present the 'Wise List' (a formulary of essential medicines for primary and specialised care in Stockholm Healthcare Region) and assess adherence to the recommendations over a 15-year period. DESIGN Retrospective analysis of all prescription data in the Stockholm Healthcare Region between 2000 and 2015 in relation to the Wise List recommendations during the same time period. S...

PROPOSAL The World Health Organization Model List of Essential Medicines and Model Formulary 2010 list deferoxamine (DFO) as the treatment of choice for both acute and chronic iron poisoning. The Model Formulary currently does not designate any orally administered agents for the chelation of iron. It is proposed that deferasirox be considered the oral chelator of choice in the treatment of chro...

PURPOSE To investigate the use of the WHO EML as a tool with which to evaluate the evidence base for the medicines on the national insurance coverage list of the Croatian Institute of Health Insurance (CIHI). METHODS Medicines from 9 ATC categories with highest expenditures from 2012 CIHI Basic List (n = 509) were compared with 2011 WHO EML for adults (n = 359). For medicines with specific in...