Introduction and Aim: The outbreak of Covid-19 pandemic since December 2019 has raised serious global health concern. Because rapid human to transmission non-availability clinically proven drugs or vaccines, this created a great threat mankind. Many naturally derived molecules are being investigated for the treatment Covid-19. Ocimum americanum is one such significant medicinal plant possessing...

With current progress in science, there is growing interest developing and applying Physiologically Based Kinetic (PBK) models chemical risk assessment, as knowledge of internal exposure to chemicals critical understanding potential effects vivo. In particular, a new generation PBK being developed which the model parameters are derived from silico vitro methods. To increase acceptance use these...

The intake of known dietary carcinogens was compiled and the cancer risk was estimated on the basis of carcinogenic potencies in animals as derived from the Carcinogenic Potency Database by Gold and co-workers. The total cancer risk was compared with the number of cancer cases attributed by epidemiologists to dietary factors (one-third of all cancer cases, i.e. approximately 80,000 per one mill...

Frequent use of synthetic larvicides has led to the development of resistance in many species of mosquitoes as well as risk of environmental pollution. Recently, encapsulating essential oils (EOs) in surfactants or polymers is being employed as an approach to control the volatility of EOs as green larvicides. In this research, components of tarragon (Artemisia dracunculus) essential oil were id...

Ocimum plants are of great interest to traditional medicine in the history several civilizations, particularly terms chronic human diseases. Essential oils obtained from this genus have also been used as therapeutic agents. In present work, two species Djibouti, basilicum L. and americanum L., were subjected hydrodistillation obtain their essential oils. Gas chromatography-mass spectrometry was...

Background: Tagetes lucida Cav (T. lucida) is an herbaceous plant from the family Asteraceae, native to Mexico, Guatemala, and other Mesoamerican countries. Their common names are: (i) Spanish names: “hierbanís”, “jericón”, “pericón vomol”, “Santa María”, “cuchrucumín”, “falso hipericón”, “hierba añil”, “pericón”, “periquillo”; (ii) indigenous “ichka”, “cuahuyauhtli”, “yahuhtli”, “naná uarhi”, ...

The study of the biosynthesis of secondary metabolites and the genes involved in these processes has been greatly facilitated by novel genomic approaches developed during the last years. Many of the biosynthetic pathways dedicated to secondary metabolism, and the enzymes involved in these pathways, have apparently evolved from the much better studied primary biosynthetic pathways. Therefore by ...