BACKGROUND The interaction of alcohol and testosterone has long been of interest, mainly due to the effect of alcohol on aggression and sexual behavior. To date, there have been very few, if any, studies examining the effect of acute alcohol administration on testosterone concentrations in the brain. The administration of 1,1-dideuteroethanol ([1,1-2H2]ethanol) provided the opportunity to trace...

A Rh porphyrin on carbon black was shown to catalyze the electro-oxidation of several aliphatic alcohols (ethanol, 1-propanol, and 2-propanol) and benzyl alcohols. The overpotentials for alcohol oxidation were very low. The reaction mechanism and substrate specificity are discussed.

This paper reported the fabrication of ternary metallic PtPdBi hollow nanocatalyst through a facile, one-pot, wet-chemical method by adopting sodium borohydride and polyvinylpyrrolidone as reducing agent and surfactant directing agent, respectively. The hollow structure offers novel morphology and large surface areas, which are conducive to enhancing the electrocatalytic activity. The electroca...

The slow, incomplete oxidation of methanol and ethanol on platinum-based anodes as well as the high price and limited reserves of Pt has hampered the practical application of direct alcohol fuel cells. We describe the electrocatalysts consisting of one Pt monolayer (one atom thick layer) placed on extended or nanoparticle surfaces having the activity and selectivity for the oxidation of alcohol...

the aim of this study is extraction of phenolic compounds from walnut leaves of touyserkani variety with two extraction methods (traditional method and with microwave assisted extraction (mae)) and evaluation of their antioxidant activity. total phenolic contents and antioxidant properties of aqueous, methanol (80%) and ethanol (50%) extracts in different times was determined. at the next stage...

A cloned mouse liver cell model (NCTC 1469) treated with either ethanol or one of its metabolites, acetaldehyde or acetate, was used to study proline uptake. Beginning with the stationary phase of cell growth, 14C-proline uptake was markedly accelerated by both ethanol and acetaldehyde (p less than 0.001). When ethanol treatment was combined with 4-methyl pyrazole so as to block ethanol oxidati...

Clinical and biomedical studies sustains the notion that early ontogeny is a vulnerable window to the impact of alcohol. Experiences with the drug during these stages increase latter disposition to prefer, use or abuse ethanol. This period of enhanced sensitivity to ethanol is accompanied by a high rate of activity in the central catalase system, which metabolizes ethanol in the brain. Acetalde...

The corrosion of zero-valent iron (Fe0(s)) by oxygen (O2) can lead to the oxidation of organic compounds. To gain insight into the reaction mechanism and to assess the nature of the oxidant, the oxidation of methanol, ethanol, 2-propanol, and benzoic acid by the reaction of nanoparticulate zero-valent iron (nZVI) or ferrous iron (Fe[II]) with O2 in the absence of ligands was studied. At pH valu...

A unique Pd nanoparticle loaded hierarchically porous graphene network was successfully prepared through multiple synergistic interactions. The obtained architectures as electrocatalysts exhibit significantly higher activity and durability for ethanol oxidation than commercial Pd/C catalysts.

BACKGROUND Epidemiological evidence has been presented for an increased risk of development of colon cancer after chronic alcohol abuse. Alcohol is degraded by cytosolic alcohol dehydrogenases that also are capable of retinol oxidation. Inhibition of retinol oxidation to retinoic acid has been shown to occur in parallel with profound impairment of intracellular retinoid signal transduction and ...