I argue against two popular claims. The first is a descriptive, empirical claim about the nature of ordinary human experience which I call the psychological Narrativity thesis (PNT). According to PNT, 'each of us constructs and lives a "narrative" … this narrative is us, our identities' (Sacks O. The Man Who Mistook His Wife for a Hat. London: Duckworth; 1985, 110). The second is a normative, e...

As evidenced by high-throughput sequencers, genomic technologies have recently undergone radical advances. These technologies enable comprehensive sequencing of personal genomes considerably more efficiently and less expensively than heretofore. These developments present a challenge to the conventional framework of biomedical ethics; under these changing circumstances, each research project ha...

BACKGROUND For ethical approval of a multicentre study in Canada, investigators must apply separately to individual Research Ethics Boards (REBs). In principle, the protection of human research subjects is of utmost importance. However, in practice, the process of multicentre ethics review can be time consuming and costly, requiring duplication of effort for researchers and REBs. We used our ex...

Marine bacterial communities are resistant to elevated carbon dioxide levels. Environmental Microbiology Reports, 6 (6). The NERC and CEH trademarks and logos ('the Trademarks') are registered trademarks of NERC in the UK and other countries, and may not be used without the prior written consent of the Trademark owner. Summary 31 It is well established that the release of anthropogenic derived ...

One of the fundamental ethical concerns about biomedical research is that it frequently exposes participants to risks for the benefit of others. To protect participants' rights and interests in this context, research regulations and guidelines set out a mix of substantive and procedural requirements for research involving humans. Risk thresholds play an important role in formulating both types ...

Eiko Nemitz,1,2 Jose L. Jimenez,3 J. Alex Huffman,3 Ingrid M. Ulbrich,3 Manjula R. Canagaratna,4 Doug R. Worsnop,4 and Alex B. Guenther2 1Atmospheric Sciences, Centre for Ecology and Hydrology (CEH) Edinburgh, Bush Estate, Penicuik, Midlothian, UK 2Atmospheric Chemistry Division, National Center for Atmospheric Research, Boulder, Colorado, USA 3University of Colorado/Dept. of Chemistry and Bioc...

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conceptually traumatic brain injury (tbi) can be classified from a mechanistic perspective as: 1) closed, 2) penetrating, 3) blast, and 4) crush injuries. thus, tbi is a heterogeneous disease and each type of brain injury has different characteristic features often necessitating different approaches to management. the first edition of the guidelines for management and prognosis of penetrating b...

surgical site infections are one of the most important post-surgery complications. antimicrobial prophylaxis has been used routinely in surgeries to reduce infection incidence. however, inappropriate selection of antimicrobial agents or dosing can develop antimicrobial resistance, serious adverse reactions and prolong hospitalization. current study aimed to examine prophylactic antibiotic presc...