نتایج جستجو برای: evolution transcriptomics

تعداد نتایج: 346105  

2016
Marcus C Chibucos Sameh Soliman Teclegiorgis Gebremariam Hongkyu Lee Sean Daugherty Joshua Orvis Amol C Shetty Jonathan Crabtree Tracy H Hazen Kizee A Etienne Priti Kumari Timothy D O'Connor David A Rasko Scott G Filler Claire M Fraser Shawn R Lockhart Christopher D Skory Ashraf S Ibrahim Vincent M Bruno

Mucormycosis is a life-threatening infection caused by Mucorales fungi. Here we sequence 30 fungal genomes, and perform transcriptomics with three representative Rhizopus and Mucor strains and with human airway epithelial cells during fungal invasion, to reveal key host and fungal determinants contributing to pathogenesis. Analysis of the host transcriptional response to Mucorales reveals plate...

Journal: :The Journal of general virology 2004
Nicolas Markine-Goriaynoff Laurent Gillet James L Van Etten Haralambos Korres Naresh Verma Alain Vanderplasschen

Studies of cellular biology in recent decades have highlighted the crucial roles of glycans in numerous important biological processes, raising the concept of glycomics that is now considered as important as genomics, transcriptomics and proteomics. For millions of years, viruses have been co-evolving with their hosts. Consequently, during this co-evolution process, viruses have acquired mechan...

2015
Mareike Albert Wieland B Huttner

The human cerebral cortex controls complex cognitive behaviors. During mammalian evolution, the number of neurons increased in many lineages, requiring a larger cortical surface area to fit into a skull that did not scale proportionally. This space problem was solved by cortical folding, resulting in gyrencephalic (folded) brains. While several hypotheses have been proposed to explain cortical ...

2016
Stefano de Franciscis Laurent Metzinger Raffaele Serra

Cardiovascular disease (CD) and peripheral vascular disease (PVD) are leading causes of mortality and morbidity in western countries and also responsible of a huge burden in terms of disability, functional decline, and healthcare costs. Biomarkers are measurable biological elements that reflect particular physiological or pathological states or predisposition towards diseases and they are curre...

Journal: :Journal of Animal and Veterinary Advances 2012

Journal: :Nature Methods 2018

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