In 2001, we followed up all patients from the 1991 Olmsted County Multiple Sclerosis (MS) prevalence cohort. We found that the longer the duration of MS and the lower the disability, the more likely a patient is to remain stable and not progress. This is particularly powerful for patients with benign MS with Expanded Disability Status Scale score of 2 or lower for 10 years or longer who have a ...

Patients with malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years). The clinical profile and progression of the disease were analyzed in a Brazilian cohort of 293 patients. Twenty-five (8,53%) patients were found to have MMS and were compared with the remaining 268 (91,47%). Women...

Abstract Background Cognitive dysfunction is increasingly recognized in multiple sclerosis, even the early phase of disease. Multiple sclerosis patients with mild cognitive deficits may experience greater difficulties social contact and daily activities, irrespective physical handicap. This study aimed to estimate clinical predictors a sample Egyptian people MS. Results Significant worse perfor...

Abstract Background Poor sleep quality and disorders are more prevalent in individuals with multiple sclerosis (MS) than the general population. has been correlated worse MS outcomes. Sleep efficiency (SE) is one of most sensitive markers quality. There very little written about SE other polysomnography (PSG) parameters measures. Methods This a retrospective review 280 consecutive evaluated by ...

Results: The relapse number, Expanded Disability Status Scale (EDSS) score at initial diagnosis, and EDSS score at last visit were significantly higher in NMO patients with brain abnormalities than those in NMO patients without brain abnormalities, respectively. NMO patients with brainstem involvement had higher relapse number, EDSS score at initial diagnosis, and EDSS score at last visit than ...

Methods Twenty-four MS patients with scores ranging from 3.0 to 7.0 on the Expanded Disability Status Scale (EDSS) received four weeks of Swedish massage treatments. The Six-Minute-Walk-Test (6MWT) was used to assess their exercise capacity and leg function and the Hamburg Quality of Life in MS (HAQUAMS) instrument was used to assess changes in client QoL. These assessments were measured before...

Background: Multiple sclerosis (MS) is known to affect essentially the central nervous system; however, peripheral nerve involvement, as an additional cause of disability, has been recently noticed. Objectives: This study was aimed to perform detailed electrodiagnostic assessments in MS patients to evaluate peripheral nervous system involvement. Materials and Methods: A total of eighty MS...

OBJECTIVE To identify clinical and immunological markers associated with HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHOD 237 HTLV-I infected individuals were clinically assessed. They were classified according to the Expanded Disability Status Scale (EDSS) and Osames Motor Disability Score (OMDS). Cytokine levels were determined in HTLV-I seropositive individuals. ...