نتایج جستجو برای: extensive efforts of trans

تعداد نتایج: 21178377  

Journal: :Genetics and molecular research : GMR 2014
C Wu T Wang J Wang B Qu H Wang Y Hu

Small cell lung cancer (SCLC) is an aggressive disease, in which more than 80% of patients present distant metastases at the time of first diagnosis. Chemotherapy is considered as the main treatment of extensive disease of SCLC (ED-SCLC), while the role of radiotherapy in the treatment of ED-SCLC is controversial. A case-control study was undertaken of patients diagnosed as ED-SCLC between 2004...

Journal: :Lung cancer 2016
Timur Mitin Aditya Jain Catherine Degnin Yiyi Chen Mark Henderson Charles R Thomas

OBJECTIVES Current National Comprehensive Cancer Network (NCCN) guidelines recommend thoracic consolidation radiation therapy (TCRT) for patients with Extensive Stage Small Cell Lung Cancer (ES-SCLC) with response to systemic chemotherapy, based on two randomized clinical trials, which varied in patient selection and radiation therapy doses administered. The current pattern of practice among US...

اشراقی, محسن , بنازاده, محمد , نویان اشرف, محمدعلی ,

Background: Acute Necrotizing Mediastinitis (ANM) is a lethal disease that without antibiotic therapy and surgical Intervention has a mortality rate about 40% in best medical centers. With development of imaging technology (spiral CT- Scan) and shortening in time of diagnosis and surgery, the outcome and prognosis of the patients are improved. The surgical modalities are trans- cervical and tra...

2015
Manu J Dubin Pei Zhang Dazhe Meng Marie-Stanislas Remigereau Edward J Osborne Francesco Paolo Casale Philipp Drewe André Kahles Geraldine Jean Bjarni Vilhjálmsson Joanna Jagoda Selen Irez Viktor Voronin Qiang Song Quan Long Gunnar Rätsch Oliver Stegle Richard M Clark Magnus Nordborg

Epigenome modulation potentially provides a mechanism for organisms to adapt, within and between generations. However, neither the extent to which this occurs, nor the mechanisms involved are known. Here we investigate DNA methylation variation in Swedish Arabidopsis thaliana accessions grown at two different temperatures. Environmental effects were limited to transposons, where CHH methylation...

Journal: :Science 2016
B J Bjork T Q Bui O H Heckl P B Changala B Spaun P Heu D Follman C Deutsch G D Cole M Aspelmeyer M Okumura J Ye

The kinetics of the hydroxyl radical (OH) + carbon monoxide (CO) reaction, which is fundamental to both atmospheric and combustion chemistry, are complex because of the formation of the hydrocarboxyl radical (HOCO) intermediate. Despite extensive studies of this reaction, HOCO has not been observed under thermal reaction conditions. Exploiting the sensitive, broadband, and high-resolution capab...

2010
Mai Yamada Satoshi Sasaki Kentaro Murakami Yoshiko Takahashi Hitomi Okubo Naoko Hirota Akiko Notsu Hidemi Todoriki Ayako Miura Mitsuru Fukui Chigusa Date

BACKGROUND The Standard Tables of Food Composition in Japan do not include information on trans fatty acids. Previous studies estimating trans fatty acid intake among Japanese have limitations regarding the databases utilized and diet assessment methodologies. We developed a comprehensive database of trans fatty acid food composition, and used this database to estimate intake among a Japanese p...

2015
Maki Morinaga Kazuyoshi Kon Hiroaki Saito Kumiko Arai Hiromi Kusama Akira Uchiyama Shunhei Yamashina Kenichi Ikejima Sumio Watanabe

Excess consumption of trans-fatty acid could increase the risk of non-alcoholic steatohepatitis (NASH); however, treatment targeting trans-fatty acid-induced NASH has not been examined. Here we focused on the influence of trans-fatty acid intake on endoplasmic reticulum (ER) stress in hepatocytes, so we investigated the effect of the chemical chaperone 4-phenylbutyric acid (PBA), on trans-fatty...

Journal: :CoRR 2012
Rakesh Mohanty Sangita Patel Shiba Prasad Dash Burle Sharma

Various list accessing algorithms have been proposed in the literature and their performances have been analyzed theoretically and experimentally. Move-To-Front (MTF) and Transpose (TRANS) are two well known primitive list accessing algorithms. MTF has been proved to be the best performing online algorithm till date in the literature for real life inputs and practical applications with locality...

Journal: :Physical chemistry chemical physics : PCCP 2014
Qian Cao Slawomir Berski Zdzislaw Latajka Markku Räsänen Leonid Khriachtchev

We study the reaction of atomic hydrogen with formic acid and characterize the radical products using IR spectroscopy in a Kr matrix and quantum chemical calculations. The reaction first leads to the formation of an intermediate radical trans-H2COOH, which converts to the more stable radical trans-cis-HC(OH)2via hydrogen atom tunneling on a timescale of hours at 4.3 K. These open-shell species ...

Journal: :Genome research 2003
Mariano Labrador Victor G Corces

The relative position of exons in genes can be altered only after large structural mutations. These mutations are frequently deleterious, impairing transcription, splicing, RNA stability, or protein function, as well as imposing strong inflexibility to protein evolution. Alternative cis- or trans-splicing may overcome the need for genomic structural stability, allowing genes to encode new prote...

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