INTRODUCTION The P2X7 receptor plays a crucial role in bone biology and inflammation. Its main function is to promote necrotic tissue metabolism by ensuring a normal acute-phase inflammatory response. We used a mouse model to describe and compare orthodontic mechanotransduction in wild-type and P2X7 knock-out mice. METHODS By using finite element analysis, mouse orthodontic mechanics were sca...

Invasive cervical resorption is a type of external resorption rarely seen as an adverse effect after a guided tissue regeneration procedure for a periodontal condition. This case report summarizes the surgical endodontic management of an invasive cervical resorption class 4 (Heithersay) with mineral trioxide aggregate, in a mandibular incisor of a 67-year-old man. A 6-year clinical follow-up wi...

objective: osteopontin (opn) has been proposed to play a role in bone resorption. with regard to bone and cementum/dentin structural and histological similarities, it was hy-pothesized that expression of this gene might be increased in resorptive lacunae during orthodontic tooth movement. materials and methods: fixed nickel-titanium closed coil springs (dentaurum ® ) capa-ble of delivering appr...

INTRODUCTION The most frequent adverse effect of canine impaction is resorption of the adjacent incisors. The subjective image quality and the radiographic diagnostic accuracy for detection of simulated canine-induced external root resorption lesions in maxillary lateral incisors were compared among 6 cone-beam computed tomography (CBCT) systems in vitro. METHODS A child cadaver skull in the ...

introduction: the aim of this innovative study was to regenerate a condition that makes it possible to carry out researches in the field on a variety of resorption. materials and methods: in order to develop apical resorption, the root canals of selected teeth were instrumented and then drilled with #4 gates glidden drills. in the next stage, the teeth were submerged in melted rose wax up to 3 ...

introduction: tooth avulsion is a real dental emergency. if immediate replantation is not performed, the avulsed tooth may be lost due to inflammatory or replacement resorption. this animal study aimed to evaluate the bone response to the titanium coating of the root surface as an artificial barrier, and prevention of resorption of avulsed teeth. methods and materials: this experimental study w...

objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (otm) in rats. materials and methods: forty male 250-300 g sprague-dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. orthodontic appliances were ligated between the maxillary first molars and in...

A case of central odontogenic fibroma is reported. The clinical, radiological and pathological features are discussed. It is of particular interest because of its maxillary location and the severe external root resorption associated with the tumour.