BACKGROUND The effect of the extraction time (min) and temperature (°C) on the yield of betulinic acid (BA) from Zizyphus joazeiro barks using focused microwave-assisted extraction was investigated. MATERIALS AND METHODS The ethyl acetate was used as extractor solvent because it was shown to provide a betulinic acid-clean extract. A full two-level statistical factorial design was applied to d...

BACKGROUND Ziziphus jujuba Mill. is nutritious and used as food and medicine for more than two thousand years. It has many pharmacological effects, such as elimination of fatigue, dilation of blood vessels, etc. The polysaccharide in it is one of the bioactive substances. In this paper, the ultrasonic extraction effects on the yield and activity of polysaccharide were studied. RESULTS The opt...

The main purpose of this study was to optimize microwave assisted alkaline extraction of the hemicellulose, xylan, from birch wood. The simultaneous effects of process variables such as time (10 30 minutes), concentration of sodium hydroxide solution (4 8 wt%), solid to liquid ratio (1:8 to 1:20, g:mL), and sample size (5 10 g) on the temperature of the wood slurry, wood dissolution, and yield ...

In a supercritical fluid extraction (SFE) unit, one generally can change the temperature, pressure, extraction bed size, solvent flow rate, among others, in order to maximize the global yield. The morphology of the solid substrate particle can also influence the extraction efficiency, since the solvent must cross diffusive paths inside the solid particle, in order to extract specific compounds ...

The effects of process parameters on the extraction of Ginkgo biloba L. leaves with supercritical carbon dioxide were investigated. The investigated parameters include particle size (mean particle diameter 0.19, 0.467 and 1.009 mm), solvent flow rate (1.58×10, 3.22×10 and 4.16×10 kg CO2/min) and pressure (100–300 bar), which were obtained by the response surface methodology (RSM) under the foll...

Centella asiatica is a tropical medicinal plant with a long history of therapeutic uses, dermal disorders, venous insufficiency and microangiopathy. The substances of therapeutic interest are the saponin-containing triterpene acids and their sugar esters. Two bioactive components, asiatic acid and asiaticoside, were extracted from Centella asiatica using subcritical water as an extraction solve...

Exopolysacharides (EPS) produced by Lactobacillus acidophilus play an important role in food processing with its well-recognized antioxidant activity. In this study, a L. acidophilus mutant strain with high-yielding EPS (2.92±0.05 g/L) was screened by chemical mutation (0.2 % diethyl sulfate). Plackett-Burman (PB) design and response surface methodology (RSM) were applied to optimize the EPS fe...

In this study, extraction of soluble proteins from rapeseed cake using different conventional and innovative extraction processes in order to maximize the extraction yield has been investigated. Firstly, various extraction techniques including ultrasound, microwave, and percolation were tested to increase the protein recovery efficiency. Secondly, response surface methodology (RSM) using a cent...

Rhizoma Atractylodes macrocephala polysaccharides (RAMP) have been reported to have a variety of important biological activities. In this study, an ultrasonic-assisted enzymatic extraction (UAEE) was employed to obtain the highest extraction yield and strongest antioxidant activity of RAMP and optimized by a multi-response optimization process. A three-level four-factor Box-Behnken design (BBD)...

The abundant fruit hulls of tea-oil tree (Camellia oleifera) are still underutilized and wastefully discaded to pollute the environment. In order to solve this problem and better utilize the fruit hulls of C. oleifera, a microwave-assisted extraction system was used to extract their polyphenols using water as the extraction solvent. A central composite design (CCD) was used to monitor the effec...