1. Maskin LP, Diaz MF, Hlavnicka A, et al. Gastrointestinal bleeding secondary to multiple gastric plasmacytoma. Am J Clin Oncol 2008; 31: 100-1. 2. Chim CS, Wong WM, Nicholis J, et al. Hemorrhagic gastric plasmacytoma as the primary presentation in multiple myeloma. J Clin Oncol 2002; 20: 344-7. 3. Hamilton JW, McCluggage WG, Jones F, et al. Extramedullary gastric plasmacytoma. Ulster Med J 19...

Extramedullary plasmacytoma is rare in patients with diagnosed multiple myeloma. Soft tissue plasmacytoma of the gallbladder is particularly uncommon and has been described in only a handful of cases. Diagnosis of gallbladder plasmacytoma with fluorine 18-fluorodeoxyglucose (F18-FDG) positron emission tomography/computed tomography (PET/CT) has not previously been reported. We present a 65-year...

Extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP) represent a disease continuum through a multistage process of cell differentiation, survival, proliferation, and dissemination, strictly related to multiple myeloma (MM), the second most common hematological malignancy. Herein, we report two cases of recurrent oral plasmacytoma progressed to MM, in which the first clinical s...

Multiple myeloma (MM) is a relatively uncommon oncohematological condition characterized by abnormal proliferation of plasma cells. Oral manifestations MM can occur in soft and intraosseous parts. We present case 69-year-old man diagnosed with undergoing chemotherapy, referred to the dental service complaining nodular swelling maxilla. An incisional biopsy was conducted histopathological analys...

Solitary plasmacytoma (SP) is an extremely rare form of hematologic malignancy that can be classified as solitary bone plasmacytoma or solitary extramedullary plasmacytoma. Here, we report a patient who presented with progressive shortness of breath and foreign body sensation in his throat. Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) demonstrated an abno...

Extramedullary disease (EMD) is an issue for patients with multiple myeloma (MM), since extramedullary spread of MM is associated with an aggressive course and a poor prognosis. Moreover, the mechanism of EMD development is uncertain. Here, we present extensive extramedullary plasmacytoma occupying the left upper limb of a 66-year-old female patient with MM with an extremely aggressive course a...

Multiple myeloma associated with extramedullary plasmacytoma at initial presentation is rare. We describe a 45-year-old female patient with an initial presentation of low back pain and right side L5, S1 radiculopathy. There was no evidence of vertebral involvement but an epidural tumor was found later during neurosurgical intervention. The final diagnosis was immunoglobulin G, kappa multiple my...

These symptoms can include weakness, fatigue, spontaneous bleeding, and increased infection.3 As the disease progresses, hypercalcemia due to increased bone resorption is often seen.3 Commonly, patients can develop kidney involvement, resulting in renal failure.3 In this case, the patient had none of these signs and symptoms when she initially presented with visual complaints. In the literature...