The mad cow disease crisis in the United Kingdom (U.K.) was a major policy disaster. The government and public health officials failed to identify the risk to humans, created tremendous uncertainty regarding the human risks once they were identified, and undertook a series of policies that undermined public trust. In contrast, the mad cow disease risk never became a major problem in the United ...

BACKGROUND The crucial role of the hypothalamic-pituitary-adrenal axis (HPA) in stress-related homeostasis suggests dysregulated HPA involvement in the pathogenesis of post-traumatic stress disorder (PTSD), yet most studies examining linkages between HPA axis measures and PTSD have yielded null findings. One untested explanation for this inconsistency is a failure to account for simultaneous ad...

fast fracture is one of the major failure modes in brittle polymers. generally, crack growth in these polymers may occur under combined tensile-shear loading. however, the fracture test data reported previously for some dental restorative resins can not be predicted by using the available fracture criteria.in this paper, a modified fracture criterion is used for estimating the fracture load for...

BACKGROUND Gun pressurization in total knee arthroplasty (TKA) may result in better cement penetration than hand packing, leading to fewer tibial plate failures. We compared cement intrusion characteristics between vacuum mixing and gun pressurization versus hand mixing and packing in the proximal tibia among patients undergoing TKA. METHODS We analyzed 6-week radiographs from 77 consecutive ...

Impermeable barriers were inserted into the stage-20 to -21 leg bud to test whether or not such an interruption of diffusion of the proposed morphogen from the polarizing zone would result in failure of leg elements to develop anterior to the barrier. Tantalum foil was placed at somite levels 30/31 or mid-31 through the dorsoventral extent of the leg bud separating anterior from posterior mesod...

The face stability of shallow tunnels was investigated with small-scale model experiments at single gravity. Aim of the research was to detect the evolution of failure mechanisms in dense and loose soil samples with varying overburden above the tunnel. Moreover, the quality of proposed theoretical/numerical approaches for the determination of a necessary support pressure pf was assessed. The re...

Methane hydrate (MH) is a new energy resource in the 21 century. But the dissociation of MH from sediments during the MH exploration or oil/gas exploration under a hydrate layer accompanied by the softening of soils and formation of excess pore gas pressure may lead to ground failures and environmental disasters. In this study, experiments on modeling the weakening and failure of the sediment b...