Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...

Subcutaneous fat necrosis of the newborn and infant is a rare disease, with still unknown incidence, which usually occurs in term or post-term newborns that have experienced perinatal stress. It usually occurs within the fi rst six weeks of newborn’s life; however, onset of the disease may be delayed for several months. A 6-week-old female infant was admitted to our department due to failure to...

We report a case of a 53 year old female who presented with a painless mass over her left greater trochanter. Evaluation with MRI and ultimately biopsy led to a diagnosis of fat necrosis. If this diagnosis had been considered with greater confidence, a conservative approach could have been taken and biopsy avoided. In patients with lesions demonstrating classic locations and imaging features of...

Sir, Panniculitis has a multiple aetiology. One of the less common causes is trauma and hence traumatic fat necrosis. These soft tissue injuries usually appear on the shins, thighs, breasts, arms and buttocks. Women are particularly susceptible (1, 2). The initial injury is usually bruising of the skin with a haematoma, and later deeper indurated lesions can be palpated (2, 3). Traumatic pannic...

Mediastinal fat necrosis (MFN) or epipericardial fat necrosis, as it is commonly referred to in the literature, is a rare self-limiting cause of chest pain of unclear etiology. MFN affects previously healthy individuals who present with acute pleuritic chest pain. Characteristic computed tomography (CT) findings include a fat attenuation lesion with intrinsic and surrounding increased attenuati...

Subcutaneous fat necrosis of the newborn is an unusual form of panniculitis, with few cases described in medical literature. The disease affects newborns at term or post-term, with normal general health. We describe two cases of newborns affected by the disease. One of them already had lesions since birth. Also, we discuss the use of puncture for diagnostic assistance.

Objective: Persian leek is one of the most widely used herbal foods among Iranians. In this study, effects of oral administration of Persian leek on plasma and liver lipids were examined in hamster. Materials and Methods: Male Syrian hamsters were randomly divided into three groups: control (standard diet), high fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholester...

Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...

AIM To evaluate an additional rapid-acting insulin bolus on postprandial lipaemia, inflammation and pro-coagulation following high-carbohydrate high-fat feeding in people with type 1 diabetes. METHODS A total of 10 males with type 1 diabetes [HbA1c 52.5 ± 5.9 mmol/mol (7.0% ± 0.5%)] underwent three conditions: (1) a low-fat (LF) meal with normal bolus insulin, (2), a high-fat (HF) meal with n...

The introduction of microsurgery has decreased the frequency of using the pedicled transverse rectus abdominis musculocutaneous (TRAM) flap, owing to its higher incidence of fat necrosis and limitations in flap insetting (vs. the free TRAM flap). We devised an efficient method of using zones 2 and 4, based on the pedicled flap's vascular anatomy, to reduce fat necrosis and achieve superior aest...