OBJECTIVE Multidimensional computerized adaptive testing enables precise measurements of patient-reported outcomes at an individual level across different dimensions. This study examined the construct validity of a multidimensional computerized adaptive test (CAT) for fatigue in rheumatoid arthritis (RA). METHODS The 'CAT Fatigue RA' was constructed based on a previously calibrated item bank....

Introduction. Fatigue syndrome is one of the nonmotor symptoms in Parkinson's disease (PD). The aim of the study was assessment of prevalence of fatigue syndrome in PD and answering the question what are the independent risk factors connected with intensity of fatigue in PD. Methods. 114 patients with idiopathic PD (mean age 62.2 + 10.8 years) were enrolled. The fatigue was assessed according t...

BACKGROUND Fatigue is a common symptom in patients with multiple sclerosis (MS). It has significant negative effects on the quality of life of patients with the condition. There are few therapeutic modalities for fatigue, which are also usually not sufficiently effective. The aim of this study was to evaluate the efficacy of acupuncture on this common symptom of patients with MS. METHODS In t...

OBJECTIVES Rheumatoid arthritis (RA) is a systemic disease of connective tissue characterised by chronic course with periods of exacerbation and remission. Even in the early stages of the disease patients report the occurrence of fatigue and sleep disorders. Reduced sleep quality and chronic fatigue are common among patients with rheumatoid arthritis. The aim of the research was to evaluate the...

BACKGROUND AND PURPOSE The aim of this study was to identify the clinical characteristics and potential mechanisms relevant to pathological proteins in Parkinson's disease (PD) patients who experience fatigue. METHODS PD patients (n=102) were evaluated using a fatigue severity scale and scales for motor and nonmotor symptoms. The levels of three pathological proteins-α-synuclein oligomer, β-a...

BACKGROUND Fatigue is a multidimensional problem affecting patients suffering from Parkinson's disease (PD). It is ranked as one of the most bothersome symptom of patients with Parkinson's disease. The study primarily aims to determine the presence of fatigue among clinically stable and independent Filipino patients suffering from idiopathic PD. METHODS This study is a prospective cross-secti...

OBJECTIVE To examine the reliability (stability) and sensitivity of the Bristol Rheumatoid Arthritis Fatigue scales (BRAFs) and patient-reported outcome measures (PROMs) developed to capture the fatigue experience. The Multi-Dimensional Questionnaire (BRAF-MDQ) has a global score and four subscales (Physical Fatigue, Living with Fatigue, Cognitive Fatigue and Emotional Fatigue), while three num...

We conducted a double-blind randomized placebo controlled trial to evaluate the impact of Lemon balm (Melissa officinalis L.) on the bleeding and systemic manifestations of menstruation. A total of 90 students were randomly assigned to treatment or placebo group. Bleeding and systemic manifestations were evaluated with a menstrual pictogram and multidimensional verbal scale before and during 2 ...

fatigue is recognized as one of the most disabling and frequent symptoms of multiple sclerosis (ms). amantadine appears to have some proven ability to alleviate the fatigue in ms. the aim of this study was to assess the efficacy of co-administration of amantadine and aspirin for the treatment of fatigue in multiple sclerosis. forty-five ambulatory patients aged 20–50 years with a diagnosis of m...

Aim: The Checklist of Individual Strength (CIS20) is a well validated measure of fatigue severity, which has been adapted in several languages. As Portuguese is one of the most widely spoken languages in the world it is important to have a Portuguese adaptation of the CIS20.Method: Four hundred and thirty healthy Portuguese adults and 89 patients with chronic fatigue (CF) filled out the Portugu...