A noninvasive method to determine postprandial fatty acid tissue partition may elucidate the link between excess dietary fat and type 2 diabetes. We hypothesized that the positron-emitting fatty acid analog 14(R,S)-[(18)F]fluoro-6-thia-heptadecanoic acid ((18)FTHA) administered orally during a meal would be incorporated into chylomicron triglycerides, allowing determination of interorgan dietar...

The chemical and physical characteristics of Malaysian palm kernel and its products are discussed in this article. The main products derived from palm kernel are palm kernel oil, palm kernel olein and palm kernel stearin whereas the by-products are palm kernel meal and palm kernel fatty acid distillate. The major composition of the kernel is oil (49%), followed by carbohydrate (26.1%), protein ...

Some populations are recommended to consume low-fat dairy, although the evidence behind replacing high-fat with dairy products is limited. This exploratory sub-study investigated effect of cheese different fat content on postprandial changes in type-2-diabetes risk markers. Following 12-week or jam intake, a 4 h meal test was conducted 37 participants. Test meals included bread and either: 80 g...

BACKGROUND Adjustments of carbohydrate intake and oxidation occur in both normal-weight and overweight individuals. Nevertheless, the contribution of carbohydrates to the accumulation of fat through either reduction of fat oxidation or stimulation of fat synthesis in obesity remains poorly investigated. OBJECTIVE The objective of this study was to assess the postprandial metabolic changes and...

Few studies have examined short term responses to the different contents of carbohydrate or fat in the meal, although long term effects of the high fat meal have been considered as compound risk factor for metabolic disorders. The aim of this study was to investigate the postprandial changes of plasma glucose, insulin and lipids upon intakes of high carbohydrate or high fat meal in young health...

The thermogenic response to food (TRF) and substrate oxidation were studied in 12 endurance-trained and 13 untrained female subjects. Energy expenditure and substrate oxidation were calculated by indirect calorimetry before and for 6 h after an oral test meal and after the same meal given intragastrically on a separate occasion. The TRF was calculated after the oral meal, the obligatory compone...

Epidemiological data suggesting benefits of increased meal frequency on CHD risk and lipid and lipoprotein levels may be flawed because of biases associated with the method of data collection. In normolipidaemic individuals increasing meal frequency from three to six or more meals daily over a period of several weeks appears to be associated with reduced levels of total and LDL-cholesterol, pos...