PURPOSE The aim of this study was the systematic image quality evaluation of coronary CT angiography (CTA), reconstructed with the 3 different levels of adaptive iterative dose reduction (AIDR 3D) and compared to filtered back projection (FBP) with quantum denoising software (QDS). METHODS Standard-dose CTA raw data of 30 patients with mean radiation dose of 3.2 ± 2.6 mSv were reconstructed u...

OBJECTIVE To evaluate the effect of adaptive iterative dose reduction (AIDR) on image noise and image quality as compared with standard filtered back projection (FBP) in 320-detector row CT coronary angiography (CTCA). METHODS 50 patients (14 females, mean age 68 ± 9 years) who underwent CTCA (100 kV or 120 kV, 400-580 mA) within a single heartbeat were enrolled. Studies were reconstructed wi...

Human folate-binding proteins (FBPs) are single chain glycoproteins that contain a high affinity binding site for folates and methotrexate and occur in a soluble or membrane-associated form. The membrane-associated FBP is involved in the uptake of physiologic folates and methotrexate. In this study, human FBP cDNA clones were isolated from human malignant nasopharyngeal carcinoma (KB) cell and ...

Limited angle problem is a challenging issue in x-ray computed tomography (CT) field. Iterative reconstruction methods that utilize the additional prior can suppress artifacts and improve image quality, but unfortunately require increased computation time. An interesting way is to restrain the artifacts in the images reconstructed from the practical filtered back projection (FBP) method. Frikel...

UNLABELLED The purpose of this study was to investigate the quantitative properties and effects of ordered-subset expectation maximization (OSEM) on kinetic modeling compared with filtered backprojection (FBP) in dynamic PET studies. Both phantom and patient studies were performed. METHODS For phantom studies dynamic two-dimensional emission scans with 10-min frames and 20-min scan intervals ...

Introduction:Low-pass filters eliminate noise, and accordingly improve the quality of filtered back-projection (FBP) in the reconstruction of single photon emission computed tomography (SPECT) images. This study aimed at selection of an optimum low-pass filter for FBP reconstruction of SPECT images of small structures. Material and Methods:Sp...

BACKGROUND AND PURPOSE Iterative reconstruction of CT images is characterized by reduced image noise and may allow reduction in radiation exposure. We investigated the influence of an IRT technique on image quality and radiation dose savings when applied to temporal bone CT. MATERIALS AND METHODS Based on the typical image quality level of adult subjects using routine radiation dose and FBP, ...

One of the major limitations to the immunotherapy of ovarian carci noma based on the use of anti-CD3/antitumor bispecific monoclonal an tibodies (bi-inAb) is the need for preactivation of effector cells ex vivo, because cross-linking of the T cell receptor-CD3 complex per se may lead to T..cellunresponsiveness or even apoptosis. The bi-mAb OCITR, which recognizes the folate-binding protein (FBP...

BACKGROUND AND PURPOSE IR has recently demonstrated its capacity to reduce noise and permit dose reduction in abdominal and thoracic CT applications. The purpose of our study was to assess the potential benefit of IR in head CT by comparing objective and subjective image quality with standard FBP at various dose levels. MATERIALS AND METHODS Ninety consecutive patients were randomly assigned ...

OBJECTIVE This work aims to explore the effects of adaptive statistical iterative reconstruction (ASiR) and model-based iterative reconstruction (MBIR) algorithms in reducing computed tomography (CT) radiation dosages in abdominal imaging. METHODS CT scans on a standard male phantom were performed at different tube currents. Images at the different tube currents were reconstructed with the fi...