A hierarchical multistage method (HMM) for digital clemultiplexing of an FDM signal composed of L adjacent SCPC signals is described; L is (preferably) a power of two, here L=32. This I-IMM approach to FDM dernultiplexing applies bandpass sampling and is based on the processing of complexvalued signals by linear-phase FIR filters, where at any stage of processing the respective signals are alwa...

BACKGROUND Functional diffusion mapping (fDM) is a cancer imaging technique that uses voxel-wise changes in apparent diffusion coefficients (ADC) to evaluate response to treatment. Despite promising initial results, uncertainty in image registration remains the largest barrier to widespread clinical application. The current study introduces a probabilistic approach to fDM quantification to over...

Abstract:   In this paper, the finite difference method (FDM) is applied to investigate the stability analysis and buckling load of columns with variable flexural rigidity, different boundary conditions and subjected to variable axial loads. Between various mathematical techniques adopted to solve the equilibrium equation, the finite difference method, especially in its explicit formulat...

The aim of this work was to explore the feasibility of using fused deposition modelling (FDM) 3D printing (3DP) technology with hot melt extrusion (HME) and fluid bed coating to fabricate modified-release budesonide dosage forms. Budesonide was sucessfully loaded into polyvinyl alcohol filaments using HME. The filaments were engineered into capsule-shaped tablets (caplets) containing 9mg budeso...

Like many other additive manufacturing processes, FDM process is driven by a moving heat source, and temperature history plays an important role in determining the mechanical properties and geometry of the final parts. Thermal simulation of FDM is challenging due to geometric complexity of manufacturing process and inherent computational complexity which requires numerical solution at every tim...

Fused deposition modeling (FDM) additive manufacturing has been intensively used for many industrial applications due to its attractive advantages over traditional manufacturing processes. The process parameters used in FDM have significant influence on the part quality and its properties. This process produces the plastic part through complex mechanisms and it involves complex relationships be...

The development of myopia is associated with decreased ocular scleral collagen synthesis in humans and animal models. Collagen synthesis is, in part, under the influence of cyclic adenosine monophosphate (cAMP). We investigated the associations between cAMP, myopia development in guinea pigs, and collagen synthesis by human scleral fibroblasts (HSFs). Form-deprived myopia (FDM) was induced by u...

The rapid printing of 3D parts with desired electrical properties enables numerous applications. Fused deposition modeling (FDM) using conductive thermoplastic composites has been a valuable approach for such fabrication. The parts produced by FDM possess various controllable structural features, but the effects of the structural features on the electrical properties remain to be determined. Th...