Chlamydial disease continues to be one of the main factors threatening the long-term survival of the koala (Phascolarctos cinereus). Despite this, large epidemiological studies of chlamydial infection and disease in wild koala populations are lacking. A better understanding of the prevalence, transmission and pathogenesis is needed to improve control measures, such as the development of vaccine...

A patient with rabies presented with penile hypersensitivity and recurrent ejaculation. This preceded the more classical manifestations such as hydrophobia and aerophobia by approximately 8 hours. A review of the literature reveals that a variety of urogenital symptoms may rarely occur in rabies. Ours is however the first report documenting the occurrence of these symptoms at the onset of the d...

we report a case of human urogenital myiasis in an 86-year-old rural man with a penil ulcer and numerous alive and motile larvae from urethra and glans penis. entomological studies on adult flies showed the larvae were lucilia sericata   and wohlfahrtia magnifica . the clinical presentation and treatment strategies are discussed.

BACKGROUND Urogenital mycoplasmas are potentially pathogenic species causing genitourinary tract infections that may be initially asymptomatic but can progress and lead to severe complications and threaten reproductive health. However, the overall prevalence rate of this bacterium and its probable impacts on fertility potential have yet to be determined. METHODS We searched both English and P...

The prostate develops in the urogenital sinus (UGS) under the influence of androgens. Whilst free androgens can enter the cell to activate the androgen receptor and induce prostate development, approximately 98.5% of androgens in plasma are bound to binding proteins such as sex hormone binding globulin (SHBG). There is increasing evidence that an alternative pathway for androgens to enter targe...

Urogenital system development in mammals requires the coordinated differentiation of two distinct tissues, the ductal epithelium and the nephrogenic mesenchyme, both derived from the intermediate mesoderm of the early embryo. The former give rise to the genital tracts, ureters and kidney collecting duct system, whereas mesenchymal components undergo epithelial transformation to form nephrons in...

Müllerian duct regression is a complex process which involves the AMH signalling pathway. We have previously demonstrated that besides AMH and its specific type II receptor (AMHRII), BMPR-IA and Smad5 are two essential factors implicated in this mechanism. Mothers against decapentaplegic homolog 4 (Smad4) is a transcription factor and the common Smad (co-Smad) involved in transforming growth fa...

Introduction: New and emerging trends in the causation of urogenital rectovaginal lesions, changing patterns behavior female patients with diseases were observed. The aim this study is to determine risk factors etiology these diseases. Methods: This was a cross-sectional observational records consecutive operated on at University Port Harcourt Teaching Hospital (UPTH), Nigeria, major lesions fr...

Generating a precise cellular and molecular cartography of the human embryo is essential to our understanding of the mechanisms of organogenesis in normal and pathological conditions. Here, we have combined whole-mount immunostaining, 3DISCO clearing, and light-sheet imaging to start building a 3D cellular map of the human development during the first trimester of gestation. We provide high-res...