We prove the existence of large-data global-in-time weak solutions to a general class coupled bead-spring chain models with finitely extensible nonlinear elastic (FENE) type spring potentials for nonhomogeneous incompressible dilute polymeric fluids in bounded domain $ \mathbb{R}^d $, d = 2 or 3 $. The under consideration involves Navier–Stokes system variable density, where viscosity coefficie...

Abstract A Taylor–Galerkin finite element time marching scheme is derived to numerically simulate the flow of a compressible and nonisothermal viscoelastic liquid between eccentrically rotating cylinders. Numerical approximations governing constitutive equations are computed over custom refined unstructured grid piecewise linear Galerkin elements. An original extension DEVSS formulation for flu...

Quantification of genetic modification (GM) is often undertaken to test for compliance with the European Union GM labeling threshold in food. Different control laboratories will often use common validated methods, but with different models of real-time PCR machines. We performed two separate ring trials to evaluate the relative precision and accuracy of different types of real-time PCR machines...

Functional studies of resident microglia require molecular tools for their genetic manipulation. Here we show that microRNA-9-regulated lentiviral vectors can be used for the targeted genetic modification of resident microglia in the rodent brain. Using transgenic reporter mice, we demonstrate that murine microglia lack microRNA-9 activity, whereas most other cells in the brain express microRNA...

Dale Pearse School of Agricultural & Resource Economics, University of Western Australia A choice modeling approach was used to identify consumer preferences for various hypothetical forms of genetic modification in beer, using a sample from Western Australia. It was found that respondents were equally averse to first-generation modification in either plants or microorganisms but were willing t...

The Three Rs are the main principles used by Animal Ethics Committees in the governance of animal experimentation, but they appear not to cover some ethical issues that arise today. These include: a) claims that certain species should be exempted on principle from harmful research; b) increased emphasis on enhancing quality of life of research animals; c) research involving genetically modified...

Public opposition to genetic modification (GM) technology in the food domain is widespread (Frewer et al., 2013). In a survey of U.S. residents representative of the population on gender, age, and income, 64% opposed GM, and 71% of GM opponents (45% of the entire sample) were "absolutely" opposed-that is, they agreed that GM should be prohibited no matter the risks and benefits. "Absolutist" op...