Ferulago angulata is a medicinal plant that is traditionally known for its anti-inflammatory and antiulcer properties. The present study was aimed to evaluate its anticancer activity and the possible mechanism of action using MCF-7 as an in vitro model. F. angulata leaf extracts were prepared using solvents in the order of increasing polarity. As determined by MTT assay, F. angulata leaves hexa...

Ferulago angulata leaf hexane extract (FALHE) was found to be a potent inducer of MCF7 cell apoptosis. The aims of the present study were to investigate the in vivo chemopreventive effect of FALHE in rats, to identify the contributing anticancer compound in FALHE and to determine its potential mechanism of action against MCF7 cells. Thirty rats harboring LA7-induced breast tumors were divided i...

Background: A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. Objective: To investigate the NO modulatory activity of the extracts of several medicinal plants native to Iran including Dracocephalum kotschyi, Linum persicum, Dionysia termeana, Salvia mirzayanii, F...

- Finding the most important medicinal herbs in Semirom. - Determination of major diseases in Semirom. - Determination of medicinal herb successes on diseases treatment. This study was a measuremental study in 2002 based on filled questionnaire distributed among the Semirom people. - 30 regional species of medicinal herbs have been found for remediation of diseases. - More than 80 percent of Se...

- Finding the most important medicinal herbs in Semirom. - Determination of major diseases in Semirom. - Determination of medicinal herb successes on diseases treatment. This study was a measuremental study in 2002 based on filled questionnaire distributed among the Semirom people. - 30 regional species of medicinal herbs have been found for remediation of diseases. - More than 80 percent of Se...

Ferulago macrocarpa (Fenzl) Boiss. commonly known as Chavil e Roshanball in Persian is a medicinal and aromatic plant from the Apiaceae family that grows in the west of Iran. The aim of this study was to investigate the phytochemical components, phenolic contents, antioxidant and antibacterial activities of hydroalcoholic extracts of F. macrocarpa flower and leaf from Lorestan...