Objective(s): Oleate can be produced through de novo synthesis, which contributes to biological processes and signaling pathways. However, the role of this non-essential fatty acid in hepatic development remains unclear. The current study aimed to evaluate the influence of early oleate deficiency induced by the inhibitor of de novo oleate synthesis MF-438 on fetal rat ...

OBJECTIVE To describe a new sign of cleft lip and palate (CLP), the maxillary gap, which is visible in the mid-sagittal plane of the fetal face used routinely for measurement of nuchal translucency thickness. METHODS This was a retrospective study of stored images of the mid-sagittal view of the fetal face at 11-13 weeks' gestation in 86 cases of CLP and 86 normal controls. The images were ex...

Prenatal exposure to alcohol (ethanol) results in a continuum of physical, neurological, behavioral, and learning defects collectively grouped under the heading Fetal Alcohol Spectrum Disorder (FASD). Fetal Alcohol Syndrome [4] (FAS) was first defined in 1973 as a condition characterized by preand postnatal growth deficiencies, facial abnormalities, and defects of the central nervous system [5]...

Background: Delayed detection of congenital heart diseases in low- and middle-income countries (LMICs) contributes to the poor outcome infants with cardiac anomalies. Fetal echocardiography (FE) can detect defects in-utero as early 18th gestational week (GA), giving parents medical professionals time prepare for baby's delivery appropriate treatment. University College Hospital, Nigeria, is one...

Prenatal exposure to alcohol (ethanol) results in a continuum of physical, neurological, behavioral, and learning defects collectively grouped under the heading Fetal Alcohol Spectrum Disorder (FASD). Fetal Alcohol Syndrome [4] (FAS) was first defined in 1973 as a condition characterized by preand postnatal growth deficiencies, facial abnormalities, and defects of the central nervous system [5]...

Prenatal exposure to alcohol (ethanol) results in a continuum of physical, neurological, behavioral, and learning defects collectively grouped under the heading Fetal Alcohol Spectrum Disorder (FASD). Fetal Alcohol Syndrome [4] (FAS) was first defined in 1973 as a condition characterized by preand postnatal growth deficiencies, facial abnormalities, and defects of the central nervous system [5]...

Isotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal abnormalities including cleft lips, ear and eye defects, and mental retardation [5]. Isotretinoin is commonly called by its trade name Accutane, and it's a chemical compound derived from vitamin A, also called retinoic acid. Doctors prescribe isotretinoi...

BACKGROUND Fetal alcohol syndrome (FAS) is a preventable birth defect, easiest to recognize in children two through eleven years and more difficult to recognize in newborns. In New York State, two systems ascertain FAS cases, the statewide birth defects registry and the Fetal Alcohol Syndrome Surveillance Network (FASSNet) system. The accuracy of FAS reports to the birth defects registry was as...

Prenatal exposure to alcohol (ethanol) results in a continuum of physical, neurological, behavioral, and learning defects collectively grouped under the heading Fetal Alcohol Spectrum Disorder (FASD). Fetal Alcohol Syndrome [4] (FAS) was first defined in 1973 as a condition characterized by preand postnatal growth deficiencies, facial abnormalities, and defects of the central nervous system [5]...

Fetal cardiac function has been shown to be a marker of disease severity in many conditions, including intrauterine growth restriction, congenital heart defects or disease (CHD), twin-to-twin transfusion syndrome, idiopathic hydrops, fetal arrhythmias, and others. It is often targeted for evaluation of patient management, for providing complete and accurate diagnoses in CHD, for patient counsel...