background: the discovery of circulating fetal dna in maternal blood led to the discovery of new strategies to perform noninvasive testing for prenatal diagnosis. objective: the purpose of the study was to detect fetal aneuploidy at chromosomes 13, 18, 21, x, and y by analysis of fetal cell-free dna from maternal blood, without endangering pregnancy. materials and methods: this retrospective st...

a full termed local ewe with the history of continuous straining with labored breathing for last 24 hours was presented. the animal was disinclined to move with tense and round abdomen which developed rapidly during last two weeks. caesarean section revealed hydrallantois accompanied by multiple fetal congenital abnormalities. the ewe was under observation for four weeks. metritis developed 12 ...

objective: the purpose of the present study was to verify the ultrastructural characteristics of cultured mouse preantral follicles from fresh and vitrified –warmed ovarian tissues. materials and methods: the ovaries of 14-day-old mice (n = 5) were vitrified using a mixture of ethylene glycol, ficoll 70 and sucrose. the preantral follicles were isolated and cultured in α-minimum essential mediu...

Cellular differentiation induces various morphological changes, including elongation, in mitochondria. Preimplantation embryos have round-shaped mitochondria, characteristic of undifferentiated cells. However, there is controversy regarding the precise mitochondrial morphology blastocyst embryos, which are generated from two cell lineages : inner mass (ICM) and differentiated trophectoderm (TE)...

If your body were a train, what would give it the power to move? The food you eat, which is burned by train’s engine. Do know how many engines has? Thousands of millions! They are called mitochondria. Mitochondria tiny structures contained within cells that burn food, providing energy. each mitochondrion due its own gearwheel: circular mitochondrial DNA. There gears in mitochondrion. Together, ...

glaucoma is the second leading cause of irreversible blindness and a neurodegenerative disease with a complex pathogenesis. increasing evidence suggests that oxidative stress and mitochondrial dysfunction have crucial roles in most neurodegenerative diseases such as glaucoma. the conventional clinical treatment for glaucoma is lowering the intraocular pressure (iop). some patients have normal i...

Common techniques for the treatment of Hepatocellular carcinoma (HCC) have not been successful, and thus the design and discovery of new compounds with better anti-cancer function are needed. Snake venom is among the most important compounds used by researchers to the treatment of various cancers. This study was designed to evaluate the toxicity effect of Persian Gulf snake venom (Enhydrina sch...

Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds used as antioxidant agents. This study aimed to investigate compare the effects fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials Methods: In this regard, mitochondria were isolated from 27 male Wistar rats (220-250 g). The cultured different doses f...

The number of people with neurodegenerative disease continues to increase every year. A new perspective is needed overcome this disease. In review, researchers collected information about dysfunctional energy in diseases driven by mitochondria. Mitochondrial dysregulation can cause damage the neuron system. amount and interaction α-synuclein SAMM50 GABARAPL1 mitochondria one factors causing As ...