Optically pumped magnetometers (OPMs) based on lasers and alkali-metal vapor cells are currently the most sensitive non-cryogenic magnetic field sensors. Many applications in neuroscience and other fields require high-resolution, high-sensitivity magnetic microscopic measurements. In order to meet this demand we combined a cm-size spin-exchange relaxation-free (SERF) OPM and flux guides (FGs) t...

We report a convenient method to create a three-dimensional micro-rotational fluidic platform for biological applications in the direction of a vertical plane (out-of-plane) without contact in an open space. Unlike our previous complex fluidic manipulation system, this method uses a micro-rotational flow generated near a single orifice when the solution is pushed from the orifice by using a sin...

1.1 Micro injection molding process Since end of 60s’ last century, with the booming of the semi-conductive materials processing technologies related to IC (Integrated Circuits) industry, parts or components in micro-scale which is hard to see with naked eyes stepped into the attention of scientists. Thereafter, the various functional micro systems were rapidly widely used in different areas, s...

The combination of micro synthetic structures with bacterial flagella motors represents an actual trend for the construction of self-propelled micro-robots. The development of methods for fabrication of these bacteria-based robots is a first crucial step towards the realization of functional miniature and autonomous moving robots. We present a novel scheme based on optical trapping to fabricate...

Swimming micro robots that mimic micro organisms have a huge potential in biomedical applications such as opening clogged hard-to-reach arteries, targeted drug delivery and diagnostic operations. Typically, a micro swimmer that consists of a magnetic bead as its body, which is attached to a rigid helical tail, is actuated by a rotating external magnetic field and moved forward in the direction ...

This study reports a new diagnostic assay for the rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) by combing nucleic acid extraction and isothermal amplification of target nucleic acids in a magnetic bead-based microfluidic system. By using specific probe-conjugated magnetic beads, the target deoxyribonucleic acid (DNA) of the MRSA can be specifically recognized and hybrid...

Micro-channel plate ~MCP! was used to intensify the image on the fluorescent screen in reflection high-energy electron diffraction. The primary electron current could be reduced by four orders of magnitude to get the image of the same intensity as in the measurement without MCP. The reduction of electron beam enabled observation of ionic crystal surfaces without causing electrolysis and chargin...

Scaling down the size of robots enables new ways of exploring and manipulating microscale environments. Specifically in the field of biology, microrobots can be a tool for single cell analysis; such as for manipulating cells [1], measuring cell interactions [2] and cell surgery [3]. To create microrobots, we need to miniturize actuation and sensing capability to the cell scale. Bacteria have be...

Whole-cell bio-chips for functional sensing integrate living cells on miniaturized platforms made by micro-system-technologies (MST). The cells are integrated, deposited or immersed in a media which is in contact with the chip. The cells behavior is monitored via electrical, electrochemical or optical methods. In this paper we describe such whole-cell biochips where the signal is generated due ...