OBJECTIVES The goal of this study was to determine whether chronic inflammation of the vascular wall may be associated with an impaired activation of the fibrinolytic system. BACKGROUND Inflammation plays an important role in the initiation and progression of atherosclerosis, and the fibrinolytic system may prevent local thrombus formation. METHODS We included 50 patients six months after t...

PURPOSE The purpose of this study was to analyze the effects of estrogen deficiency and hormone replacement therapy (HRT) on fibrinolytic activity in a rat mode of surgically-induced menopause. METHODS Twelve-week-old, sexually mature female Sprague-Dawley rats, each weighing 200-250 g, were randomly divided into four groups: (1) sham-operated group, (2) ovariectomy group, (3) ovariectomy gro...

This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced by b-hemolytic streptococci and exerts its enzyme action indirectly by activating plasminogen. On the other hand, staphylokinase is produced by Staphylococcus aureus by stoichiometric complexation with plasmin(ogen)...

This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced by b-hemolytic streptococci and exerts its enzyme action indirectly by activating plasminogen. On the other hand, staphylokinase is produced by Staphylococcus aureus by stoichiometric complexation with plasmin(ogen)...

This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced by b-hemolytic streptococci and exerts its enzyme action indirectly by activating plasminogen. On the other hand, staphylokinase is produced by Staphylococcus aureus by stoichiometric complexation with plasmin(ogen)...

Abstract—Fibrin degradation is an important part in prevention or treatment of intravascular thrombosis and cardiovascular diseases. Plasmin like fibrinolytic enzymes has given new hope to patient with cardiovascular diseases by treating fibrin aggregation related diseases with traditional plasminogen activator which have many side effects. Various researches involving wide range of sources for...

The objective of this study was to evaluate the impact of obesity and firefighting activities on coagulation and fibrinolytic activity in relatively young, apparently healthy firefighters. Firefighters performed simulated firefighting activities for 18 minutes in a live-fire training structure. Blood samples were obtained at baseline, before firefighting, and within a few minutes of completing ...

This book describes the fibrinolytic enzymes of microbial origin that are able to dissolve endogenous thrombi in vivo. The fibrinolytic enzyme streptokinase for example, is produced by b-hemolytic streptococci and exerts its enzyme action indirectly by activating plasminogen. On the other hand, staphylokinase is produced by Staphylococcus aureus by stoichiometric complexation with plasmin(ogen)...

Objectives. We sought to examine whether the disturbed fibrinolytic system in patients with an acute coronary syndrome is associated with a reduced endothelial fibrinolytic capacity. Background. Intracoronary thrombus formation is a frequent finding in acute coronary syndromes. Systemic alterations of coagulation and fibrinolysis are known to occur, but possible disturbances of endothelial fibr...

Arterial hypoxia has been accepted as a potent stimulus to increased fibrinolytic activity in vivo. This study has shown that significant levels of arterial hypoxaemia induced in healthy volunteers by breathing a hypoxic gas mixture have failed to induce changes in the fibrinolytic enzyme system.