Despite extensive research for many years throughout the world, the etiopathogenesis of cancer still remains obscure. Oxidative stress have been associated with the risk of breast cancer. A total number of 121 subjects are studied, comprising of 35 controls, 26 fibroadenoma and 60 Breast cancer subjects. Breast cancer subjects were further divided depending on stage of the cancer. Serum levels ...

BACKGROUND In invasive ductal carcinoma (IDC), many antiapoptotic and proapoptotic genes regulate disease outcome. Hormone receptor-mediated mechanisms have also been shown to prevent apoptosis. Therefore, relations between hormone receptor status and other molecular markers need further examination. AIMS In the present study, we analyzed the expression of apoptosis-regulating genes, viz., Su...

OBJECTIVE To investigate the magnitude of breast diseases, and its frequency distribution in different age groups in Hadramout, Yemen. METHODS This is a prospective study conducted at the Central Laboratory of Ibn-Sinna Hospital, Hadramout, Yemen from January 2006 to December 2009. Patients attending surgical units for breast problems were eligible. Patients were assessed clinically and refer...

Introduction. The congenital anomalies of breast, especially the polymastia (supernumerary breast) and polythelia (supernumerary nipple), always do not fail to amuse the clinicians because of their varied presentations, associated renal anomalies, and pathologies arising from them. The axillary polymastia is a variant of ectopic breast tissue (EBT). Ectopic breast tissue can undergo the same ph...

BACKGROUND The aim of this study was to investigate the association between LAPTM4B gene polymorphism and the risk of breast cancer among Egyptian female patients. Also, measurement was done of its serum level to evaluate its significance as a diagnostic marker for breast cancer. METHODS This case control study was done on 88 breast cancer patients, 40 with fibroadenoma and 80 healthy subject...

Genesis of breast cancer is a multistage process involving accumulation of genetic alterations, but little is known about the implication of genetic alterations in benign breast disease (BBD) lesions. Among benign lesions of the breast, one of the most common is fibroadenoma. The relationship between fibroadenoma and breast cancer is not clear. Some epidemiological studies show an association w...

* Bangalore Medical College & Research Institute (BMCRI), KR Road, Bangalore, India E-mail of Corresponding Author: [email protected] Abstract Background: Fibroadenomas are one of the main benign diseases of breast. Though considered as a risk factor for development of breast cancer its reporting has been over shadowed by that of breast cancer. Early diagnosis and treatment can relieve anxi...

Background: Breast cancer is the most common malignancy in females worldwide. Several etiological factors including environmental factors have been recognized for breast cancer. Epstein Barr virus as a viral etiological factor has been proposed. So far, several studies have investigated the relationship between development of breast cancer and Epstein Barr virus, but few have been done in Iran....

An 11-year-old girl with rapidly enlarging bilateral breast lumps is reported. It was diagnosed as a case of juvenile fibroadenoma following fine needle aspiration cytology and confirmed on histopathological examination of the excised specimens.

Background: Benign breast disorders constitute the majority of complaints presented by young females to a surgical OPD. It is 10 times more common than cancerous conditions and deserves attention due its high prevalence, impact on woman’s life associated anxiety possibility some turning into conditions. divided aberrations abnormalities in development, epithelial stromal proliferations, inflamm...