We propose a new model for calculating infinite dilution diffusion coefficients for carbon dioxide and water mixtures. The model takes into account temperature dependence of the dipole moment of water and polarizability of CO2, and fits experimental CO2AH2O data at low and high pressures with an accuracy of 4.9%. Remarkably, the proposed model also accurately predicts infinite dilution diffusio...

Metoprolol succinate (MS) gastroretentive (GR) controlled release system was formulated to increase gastric residence time leading to improved drug bioavailability. Box-Behnken model was followed using novel combinations of sodium alginate (SA), sodium carboxymethylcellulose (NaCMC), magnesium alumino metasilicate (MAS) as independent variables. Floating lag time (Flag), t25, t50, t75, diffusio...

A generalized continuum framework for the theory of solute transport in fluids is proposed and systematically developed. This framework rests on the introduction of a generic force balance for the solute, a balance distinct from the macroscopic momentum balance associated with the mixture. Special forms of such a force balance have been proposed and used going back at least as far as Nernst’s 1...

Drug release from a swelling hydrogel matrix is a complicated process where diffusion of drug molecules is coupled to the swelling kinetics. The swelling influences the diffusional flux of drug molecules by increasing the diffusion coefficient and diffusional pathlength. Release of phenylpropanolamine from apoly(hydroxyethy1 methacrylate-co-methacrylic acid) hydrogel, initially at low pH, is hi...

The shear-transformation-zone (STZ) theory has been remarkably successful in accounting for broadly peaked, frequency-dependent, viscoelastic responses of amorphous systems near their glass temperatures T_{g}. This success is based on the theory's first-principles prediction of a wide range of internal STZ transition rates. Here, I show that the STZ rate distribution causes the Newtonian viscos...

This paper investigates the dynamics of a model two chemostats connected by Fickian diffusion with bounded random fluctuations. We prove existence and uniqueness non-negative global solution as well compact absorbing attracting sets for solutions corresponding system. After that, we study internal structure set to obtain more detailed information about long-time behavior state variables. In suc...

In this work, a blend of gelatin A (GA) and polyvinylpyrrolidone (PVP K30) was used for semi-solid 3D printing bone scaffold ibuprofen (IBU) delivery. The cross-linking the obtained performed with 1% glutaraldehyde (GTA) solution, followed by lyophilization. thermal mechanical properties, as well drug release profiles, kinetics prepared scaffolds were investigated. cross-linked lyophilized has ...

2 The work investigates the formulation development, evaluation and optimization of ibuprofen effervescent tablet using 3 factorial designs. The effect of variables viz. xanthan gum and sodium bicarbonate on drug release and hardness of ibuprofen effervescent tablets were analyzed and optimized. The optimized formulation showed the ibuprofen release in sustained manner over a period of 6h. The ...