The Wilms' tumour suppressor gene WT1 encodes a protein involved in urogenital development and disease. The salient feature of WT1 is the presence of four 'Krüppel'-type C(2)-H(2) zinc fingers in the C-terminus. Uniquely to WT1, an evolutionarily conserved alternative splicing event inserts three amino acids (KTS) between the third and fourth zinc fingers, which disrupts DNA binding. The ratio ...

Finger millet is an important cereal crop in Africa, where it plays role nutrition and food security. The purpose of this study was to determine the effect germination period on physicochemical properties elite finger varieties. Axum, Meba, Tadesse Tessema varieties were soaked for 24 h germinated 24, 48 72 at room temperature (23.2 ± 2.6°C) relative humidity (37.91 8.17%), before being oven-dr...

We present wide-field and high-sensitivity CO(1-0) molecular line observations toward the Cassiopeia region, using 13.7m millimeter telescope of Purple Mountain Observatory (PMO). The CO reveal a large-scale highly filamentary cloud within Galactic region 132\fdg0\,$\geq$\,$l$\,$\geq$\,122\fdg0 -1\fdg0\,$\leq$\,$b$\,$\leq$\,3\fdg0 velocity range from approximately +1 to +4 km/s. measured length...

Serotonin (5-HT) is a key regulator of mood and sexual behaviors. 5-HT reuptake inhibitors have been used as antidepressants. Really interesting new gene (RING) finger proteins have been associated with 5-HT regulation but their role remains largely unknown. Some RING finger proteins are involved in the serotonergic system, therefore, we speculate that the gene expression of RING finger protein...

A varactor with high Q factor and large tuning range is a mandatory prerequisite for a current efficient LC-tank VCO design. Commonly used varactors include the p-n junction varactors, PMOS varactors and accumulation mode (n or ptype) varactors. This paper discusses the results from the benchmarking of different two and three-terminal MOS varactor structures. The structures are first generated ...

OBJECTIVE The purpose of the present study was to identify length and landmark of proximal of A1 pulley in hand. MATERIAL AND METHOD An anatomical study of the length and landmark of A1 pulley in hand was performed in 510 fingers and thumbs from 51 preserved cadavers. There were 25 females and 26 males whose ages at the time of death ranged from 48 to 89 years. RESULTS The lengths of A1 pul...

BACKGROUND Although the pathogenesis of androgenetic alopecia is not completely understood, the roles of genetic susceptibility and androgens are well-known. A lower ratio of the second digit (index finger = 2D) to the fourth digit (ring finger = 4D) length has been hypothesized to reflect prenatal androgen exposure and/or higher sensitivity to androgens. OBJECTIVES To determine the relations...

Recent studies have revealed that human position sense relies on a massively distorted representation of hand size and shape. By comparing the judged location of landmarks on an occluded hand, Longo and Haggard (2010) constructed implicit perceptual maps of represented hand structure, showing large underestimation of finger length and overestimation of hand width. Here, we investigated the cont...

We sought to establish whether spastic hypertonia results from changes in intrinsic muscle properties or from altered stretch reflex properties. We hypothesized that finger flexor spastic hypertonia is primarily of neural origin, and that the dynamics of spastic muscle responses to stretch should therefore reflect the dynamics of muscle spindle receptor responses. In 12 stroke survivors, we rec...