The composition dependence of glass forming ability in the ternary Al-Cu-Y system is predicted by thermodynamic calculations based on the Miedema’s model and Alonso’s method. By comparing the relative energetic status of the amorphous phase versus the solid solution phase, a hexagonal composition region that energetically favoring the metallic glass formation is predicted. The glass formation d...

The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of exerting mechanical force. Here, we investigated whether synaptic forces promote the destruction of target cells. CTLs kill by secreting toxic proteases and the pore forming protein perforin into the synapse. Biophysical experiments revea...

We present a framework to design force fields that drive particles to follow a path under the physics-based animation system. In this framework, a user interactively specifies the desired path, represented by a Bezier curve using a GUI and the attraction force that drives a particle toward the target location. Then, the framework automatically defines the steering force to make a particle follo...

We analytically investigate the formation of an HII region in the accreting envelope of a newborn star. Special care is taken to examine the role of ionizing radiation force. This effect modifies velocity and density distributions and thereby affects the expansion of the HII region. As a result, the upper limit of the stellar mass imposed by the growth of an HII region around a forming star is ...

We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. The array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol(-1).