BACKGROUND Neuroimaging studies have provided evidence of abnormal frontal and temporal lobe function in schizophrenia. Frontal cortex abnormalities have been associated with negative symptoms and temporal lobe abnormalities with positive symptoms. The deficit and nondeficit forms of schizophrenia were predicted to differ in prefrontal cortical activity, but not in medial temporal lobe activity...

The frontal lobe is the largest lobe of the brain and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas.This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkable that frontal behavioural syndromes have rather uncommonly been reported in pat...

Frontal lobe epilepsy accounts for only 10-20% of the patients in surgical series, but the incidence in non-surgical patient cohorts seems to be much higher. The typical clinical presentation of the seizures includes contralateral clonic movements, uni- or bilateral tonic motor activity as well as complex automatism. The yield of surface EEG may be limited due to the difficulty in detection of ...

Frontal lobe epilepsy makes up between 20 and 30% of all partial epilepsies and is the biggest subgroup of the extratemporal lobe epilepsies. Of the patients who undergo surgery for epilepsy up to 18% have a frontal lobe focus. The aetiology of frontal lobe epilepsy is varied, clinical semiology is diverse and seizures are often frequent, disabling and refractory to treatment. Imaging and EEG f...

Objective. This study examined the relationship between neural activity and executive function (EF) by near-infrared spectroscopy (NIRS). In addition, an oral reading span test (RST) was used to explore this association. Methods. Fifteen adults participated in the study. We used the RST and simple reading as the two tasks. Results. The RST score and cortical hemodynamic response in the left inf...

OBJECTIVE This synthetic review was performed to demonstrate the utility of frontal-subcortical circuits in the explanation of a wide range of human behavioral disorders. DATA SOURCES Reports of patients with degenerative disorders or focal lesions involving frontal lobe or linked subcortical structures were chosen from the English literature. Individual case reports and group investigations ...

Patients with limited focal frontal and nonfrontal lesions were tested for visual perspective taking and detecting deception. Frontal lobe lesions impaired the ability to infer mental states in others, with dissociation of performance within the frontal lobes. Lesions throughout the frontal lobe, with some suggestion of a more important role for the right frontal lobe, were associated with impa...

AIM Comprising large areas of association cortex, the parietal lobe is part of an extensive synaptic network elaborately intertwined with other brain regions. We hypothesize that such widespread projections are responsible for producing inaccurate localisation readings on scalp EEG and clinical semiology in patients with parietal lobe epilepsies, as opposed to frontal or temporal lobe epilepsie...

On the basis of their scores on composite measures of frontal and temporal lobe function, derived from neuropsychological testing, seniors were divided preexperimentally into 4 groups. Participants studied a list of unrelated words under full attention and recalled them while concurrently performing an animacy decision task to words, an odd-digit identification task to numbers, or no distractin...

BACKGROUND Proton magnetic resonance spectroscopy (1H MRS) allows for examining brain functions in vivo in schizophrenic patients. Correlations between N-acetylaspartate (NAA) level in the frontal lobe and cognitive functions and clinical symptoms have been observed. The aim of the present study was evaluation of relationship between clinical symptoms, cognitive outcomes and brain function in 1...