The medical understanding of autism has changed since it was first defined by Kanner. Nowadays medicine identifies many medical abnormalities and diseases, which may underline or aggravate the cognitive aspect, behavioural issues and general health in autists. This includes chronic inflammation of gastrointestinal tract, dysbiosis, maldigestion, malabsorption, malnutrition, food intolerance, al...

The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism. We measured concentrations of N-acetylaspartate (NAA), choline-containing compounds (Cho), and creatine plus phosphocreatine (Cr+PCr) in the hippocampal formation by proton magnetic resonance spectroscopy in 12 non-medicated mal...

Pervasive Developmental Disorders (PPD) refers to the group of disorders characterised by delayed or inappropriate development of multiple basic functions including socialisation, communication, behaviour and cognitive functioning. The term,,autistic spectrum disorders" was established as a result of the magnitude of the intensity of symptoms and their proportions observed in all types of perva...

The linguistic profile of people with Autism spectrum disorders typically involves intact perceptual processing, accompanied by deficits in the social functions of language. In a series of three experiments, the impact of this profile on the perception of regional dialect was examined. Young adults with High-Functioning Autism exhibited similar performance to a typically developing comparison g...

OBJECTIVES Studies suggest that having a child with autism has a negative impact on maternal psychological functioning, but no large-scale, population-based studies are available. The objectives of this study were to (1) describe the psychological functioning, physical and mental health, family communication, and parenting support of mothers of a child with autism compared with other mothers on...

BACKGROUND Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also females' camouflaging. The study describes a new technique that allows automated coding of non-verbal mode of communication (gestures) and offers the possibility of objective, evaluat...

The purpose of this study was to investigate the relationship between sleep problems, gastrointestinal symptoms, social functioning, autism traits, and support on quality life (QoL) in 107 adults with spectrum disorder (ASD). Questionnaires included Autism Spectrum Quotient-10 (Adult), Multidimensional Scale Perceived Social Support, Functioning Questionnaire, Pittsburgh Sleep Quality Index, Ga...

Objectives: The incidence of stereotyped behaviors is one of the major symptoms of diagnosis of individuals with autism spectrum disorder that causes disruption in daily life. This study aimed at evaluating the effectiveness of ball exercises on the reduction of stereotypical behavior of children with autism spectrum disorder. Methods: In this study, 16 children (boys) with autism spectrum dis...

intellectual disability is a term used when a person has certain limitations in mental functioning and skills. autism is a group of developmental brain disorders, collectively called autism spectrum disorder (asd). teenagers with learning and physical disabilities are more likely to have menstrual problems compared to the general populations. the parents of a 12-year-old girl with autism spectr...

Younger siblings of children with autism spectrum disorder (ASD; high-risk siblings) exhibit lower levels of initiating joint attention (IJA; sharing an object or experience with a social partner through gaze and/or gesture) than low-risk siblings of children without ASD. However, high-risk siblings also exhibit substantial variability in this domain. The neurotransmitter dopamine is linked to ...