Objective: To evaluate spirometric patterns of respiratory disorders and their relationship with functional severity and maximal expiratory flows at low lung volumes in patients with cystic fibrosis (CF). Methods: A retrospective cross-sectional study including adolescents and adults with CF. All of the patients were submitted to spirometry. Patients were classified as having preserved respirat...

BACKGROUND most patients with moderate cognitive impairment are unable to perform forced spirometry. It has been suggested that slow vital capacity (SVC) is easier to perform than forced vital capacity (FVC) because it requires less understanding and co-ordination. We conducted a study to determine whether that assertion is correct. METHODS we studied 83 inpatients, mean age 83 years (range 6...

In a large cohort of 1034 patients with the diagnosis of definite or probable amyotrophic lateral sclerosis (ALS), the association of forced vital capacity (FVC) at baseline with (a) time to progression of 20 points in Appel ALS (AALS) score or (b) tracheostomy free survival was investigated. The median survival of ALS patients with baseline FVC <75% was 2.91 years, compared with 4.08 years for...

The study was conducted on 100 pregnant women in third trimester of uncomplicated pregnancy (Test group) and 100 age-matched non-pregnant women (Control group) in the age group of 25 to 35 years. Pulmonary function test parameters FVC, FEV1, PEFR and FEF25-75% recorded using Medspiror. The FEV1/FVC ratio was calculated. All parameters except FEV1/ FVC ratio were found to decline in the Test gro...

Measurements of dynamic force-length behavior of maximally activated strips of smooth muscle during oscillatory length changes show that force decreases well below the isometric force during the shortening phase of the oscillation. The magnitude of the decrease depends on the rate of shortening; for slower shortening, the decrease is smaller and force is larger. Modeling of expiratory flow, bas...

1. In five subjects, ten consecutive forced expiratory spirograms were recorded on each of 6 different days and the total forced expiratory time (FET) on each spirogram was measured. The mean overall coefficient of variation of the FET was 11.3% and of the ratio forced vital capacity (FVC)/FET was 8%. 2. Twenty-two subjects with probable small (less than 2 mm diameter) airway dysfunction as man...

In 2022, Poland joined the elite group of countries where CFTR modulators (mCFTR) are reimbursed. The aim this prospective study was analysis selected nutritional and pulmonary function parameters their impact on patient health-related quality life in CF children before 3 months after introduction mCFTR therapy. patients aged 2–18 consecutively enrolled program were assessed during trimonthly v...

Carrying heavy and moderate military loads in backpacks or as body armour compresses the chest, causing a change in lung function that is typical of a restrictive ventilatory impairment. It is not known if a lighter backpack load of only 6 kg, such as is typical of loads carried by students, will have a similar effect on lung function. There have been no studies examining whether backpacks of d...

The criteria of the American Thoracic Society (ATS) for determining the end-point of the forced vital capacity (FVC) maneuver were compared with an algorithm employed by a computer system (Hewlett-Packard), which yields a later end-point. The 150 subjects tested were divided into five groups of 30 on the basis of the following spirometric diagnoses: normal; small airways' obstruction (SAO); mil...