OBJECTIVE To determine the pharmacokinetics of gallium maltolate (GaM) after intragastric administration in healthy foals. ANIMALS 6 healthy neonatal foals. PROCEDURES Each foal received GaM (20 mg/kg) by intragastric administration. Blood samples were obtained before (time 0) and at 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, and 48 hours after GaM administration for determination of serum gallium ...

BACKGROUND Gallium-67 scintigraphy has been suggested as a noninvasive method to diagnose acute interstitial nephritis (AIN). However, its diagnostic performance and usefulness remain controversial. METHODS We retrospectively reviewed the charts of 76 patients who underwent gallium-67 scintigraphy for a suspicion of AIN. Patients were classified based on kidney biopsy and/or clinical probabil...

  Purpose: To recognize affective factors in delivering X-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   Materials and Methods: Since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). X-ray imaging was done to determine geometric features of liver.   Results: Rad...

We have shown that transferrin-gallium (Tf-Ga) blocks DNA synthe sis through inhibition of cellular iron incorporation and a diminution in the activity of the iron-dependent M2 subunit of ribonucleotide reductase. To examine the mechanisms of drug resistance to gallium, we developed a subline of HL60 cells (R cells) which is 29-fold more resistant to growth inhibition by gallium nitrate than th...

The deficit observed in the Gallium radioactive source experiments is interpreted as a possible indication of the disappearance of electron neutrinos. In the effective framework of two-neutrino mixing we obtain sin 2θ & 0.03 and ∆m & 0.1 eV. The compatibility of this result with the data of the Bugey and Chooz reactor short-baseline antineutrino disappearance experiments is studied. It is found...

Hydrogen adsorption on the ~234! and ~432! reconstructions of gallium arsenide ~001! has been studied by internal reflectance infrared spectroscopy and ab initio cluster calculations with density-functional theory. The calculations are made on Ga5As4H11,13, Ga4As5H11,13 , and Ga7As8H19 clusters, which model the arsenicand gallium-dimer termination of the semiconductor surface. Excellent agreeme...

Iron is an essential nutrient for many microbes. According to the "Trojan Horse Hypothesis", biological systems have difficulties distinguishing between Fe(3+) and Ga(3+), which constitutes the antimicrobial efficacy of the gallium(iii) ion. Nine novel tris(quinolono)gallium(iii) complexes and their corresponding iron(iii) analogs have been synthesized and fully characterized. Quinolone antimic...

Gallium metallic photonic crystals with 100% filling factor have been fabricated via infiltration of liquid gallium into opals of 300-nm silica spheres using a novel high pressure–high temperature technique. The electrical resistance of the Ga-opal crystals was measured at temperatures from 10 to 280K. The data obtained show that Ga-opal crystals are metallic network with slightly smaller tempe...