The effect of fermentation parameters and medium composition on the simultaneous mycelial growth and exo-polymer production from submerged cultures of Ganoderma applanatum was investigated in shake-flask cultures. The optimum initial pH for mycelial growth and exo-polymer production was 5.0 and 6.0, respectively. The optimum temperature was 25℃ and the optimum inoculum content was 3.0% (v/v). T...

This paper presents the current state of knowledge on biological activity and possible medicinal applications selected species genus Ganoderma: Ganoderma adspersum (Schulzer) Donk, applanatum (Pers.) Pat., carnosum lucidum (Curtis) P. Karst., pfeifferi Bres., resinaceum Boud. These inedible, wood-decaying fungi are pathogens that cause enzymatic decomposition wood. They a valued natural resourc...

This study was conducted to find the causes of migraine in Karachi, Pakistan and also to assess the efficacy of mushrooms (GANODERMA LUCIDUM therapy) in treatment of migraine. Migraine is an episodic headache that affects the general population. There are lots of factors that cause migraine and may include stress, exposure to light and sounds, anxiety, caffeine reduction etc. Many medicines are...

The nomenclature of Ganoderma used as a Chinese medicine is debated. A group of researchers could not amplify the DNA of type specimens and concluded the DNA was degraded irreparably. New topotypes were used as the type specimens which was premature. The use of internal amplification controls is recommended to determine if other factors were involved as alternative explanations.

Two new highly oxygenated lanostane triterpenoids, ganoderic acid AP2 (1) and ganoderic acid AP3 (2), were isolated from the fruiting bodies of the fungus Ganoderma applanatum (Ganodermataceae), along with four known analogues, ganoderenic acids A, B, D and G (3-6). The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis.