Introduction: Completion of the three-dose human papillomavirus (HPV) vaccine series has been challenging and cost may play a role. The objectives of this study were 1) to evaluate vaccine completion rates after receipt of first dose and 2) to determine factors associated with vaccine completion among women presenting at an urban, public hospital, where the vaccine was provided free of charge. ...

BACKGROUND Papillomavirus disease and associated cancers remain a significant health burden in much of the world. The current protective vaccines, Gardasil and Cervarix, are expensive and not readily available to the underprivileged. In addition, the vaccines have not gained wide acceptance in the United States nor do they provide therapeutic value. Papillomaviruses are strictly species specifi...

Cervical cancer is the second-most common cancer in women worldwide causing most cancer related deaths in women in developing countries including India. The most predominant etiological factor for cervical cancer is persistent infection of certain high-risk types of human papillomaviruses (HR-HPVs), while low-risk types are associated with benign cervical lesions and genital warts. In India, th...

BACKGROUND Cervical cancer is linked to infection of the cervix by oncogenic human papillomavirus (HPV) subtypes. The quadrivalent Gardasil vaccine (against HPV types 6, 11, 16, 18), recommended in girls 9 - 12 years of age, has been shown to be safe, immunogenic and efficacious, with minimal or no side-effects. AIM To demonstrate the capacity of school health teams to carry out vaccinations ...

Infection by human papilloma virus (HPV) attracted attention in connection with cervical cancer in humans (zur Hausen, 1996). HPV type 16 alone accounts for approximately 50% of all cases of cervical cancer. The virus icosahedral capsid is composed of the L1 major and the L2 minor proteins. L1 alone has the capacity to self-assemble into virus-like particles (VLPs) without participation of L2 o...

The aim of this paper was to measure student knowledge of HPV and risks associated with cervical cancer, explore associated factors, correlate knowledge of HPV and cervical cancer with other domains of sexual health related knowledge and estimate student self-reported rates of HPV immunisation. Data were from a nationally representative cross-sectional stratified cluster sample of year 10 and 1...

A local general practice was contracted to provide the school-based immunisation program over two years in Mount Isa, Queensland. The schedule was for female Year 10, 11 and 12 students to receive three doses of human papilloma virus (HPV) vaccination (Gardasil). This was provided as part of the broader immunisation program that involved providing Year 8 students with two doses of hepatitis B v...

OBJECTIVE To synthesise lessons learnt and determinants of success from human papillomavirus (HPV) vaccine demonstration projects and national programmes in low- and middle-income countries (LAMICs). METHODS Interviews were conducted with 56 key informants. A systematic literature review identified 2936 abstracts from five databases; after screening 61 full texts were included. Unpublished li...

A 9-month-old boy presented with a 1-day history of fever and croupy cough. He had been diagnosed with laryngomalacia at 4 months of age and treated for recurrent croup and bronchiolitis. He was <0.4th centile for weight. He had marked biphasic stridor in all positions along with tachypnoea. He showed some initial improvement with bronchodilators, steroids and antibiotics for suspected pneumoni...

Human Papillomavirus (HPV) is the most common sexually transmitted disease which can infect different parts of the body including uterus. Cervical cancer is the second most common cancer among women worldwide. The HPV-related disease appears to be increasing but treatment is limited, difficult and insufficient with high relapse rate. This growth in disease burden had made the development of two...