background: pulse wave velocity (pwv) is widely used for estimating the stiffness of an artery. v arious invasive and non-invasive methods have been developed to determine pwv over the years. in the present research , the non-invasive estimation of the pwv of large arteries was used as an index for arterial stiffness. methods: a dynamic model based on the navier-stokes equations coupled to elas...

adenosine has many of the characteristics of a regulator of cerebral blood flow and adenosine receptors change in morphine dependency. in this study the changes in adenosine receptors' responsiveness of pial vessels in the hind limb area of the sensory cortex were evaluated in morphine dependent rats (mdr) using the laser doppler flowmetry technique. adult male sprague dawley rats (250-350...

We studied the effects of increasing cardiac output by fluid loading on splanchnic blood flow in patients with haemodynamically stabilized septic shock. Eight patients (five female, 39-86 yr) were assessed using a transpulmonary thermo-dye-dilution technique for the measurement of cardiac index (CI) intrathoracic blood volume (ITBV) as a marker of cardiac preload and total blood volume (TBV). S...

UNLABELLED Recent studies have shown that ghrelin exhibits gastroprotective effects. The aim of present study was to examine the influence of ghrelin administration on the healing of chronic gastric and duodenal ulcers and to evaluate the role of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in this process. In pituitary-intact or hypophysectomized rats, chronic gastric and duode...

Gastric aminopyrine clearance was measured in human volunteers and dogs with untreated basal secretion, in human volunteers and dogs treated with secretory inhibitors, in dogs treated with histamine, and in patients with pernicious anaemia. When aminopyrine was given as a bolus to man or dog, aminopyrine clearance and the ratio aminopyrine concentration in gastric juice/aminopyrine concentratio...

Gastric necrosis is a rare entity mainly due to the rich collateral blood flow the stomach is supplied by. Acute gastric dilation is one of the described underlying causes, and although not fully understood, many potential alterations, such as vascular compression, herniation, volvulus, acute necrotizing gastritis, complications after abdominal surgery, anorexia, bulimia nervosa, trauma, exposu...

Drug absorption through the gastrointestinal tract plays a major role in determining the systemic exposure of the drugs when administered by oral route. The physicochemical properties of the drug like particle size, polymorphism, salt forms, lipophilicity and dosage form characteristics like disintegration time, dissolution time, manufacturing variables, pharmaceutical ingredients, nature and t...

BACKGROUND The purpose of this observational study was to investigate the relationship between splanchnic and renal blood flow during infrarenal aortic cross-clamp (XC) and postoperative gastrointestinal perfusion and function. METHODS Descending aortic blood flow (DABF) was continuously monitored with an oesophageal Doppler monitor (Cardio-Q, Deltex Ltd, Chichester, UK) in 31 patients underg...