Upper gastrointestinal tract (UGIT) comprises of esophagus, stomach and duodenum till the second part. Diseases affecting this region include inflammatory lesions, dysplasias, benign neoplasms malignancies. Endoscopic biopsy histopathological examination is considered as gold standard for disorders. aids in early diagnosis malignancy better patient management. Present study was conducted with a...

Hypercalcemia in patients with cancer is a common laboratory finding affecting up to 44% of that patient population. 1,25-Dihydroxyvitamin D3 mediated hypercalcemia is one of the rare mechanisms of this endocrine emergency in cancer patients. It is even rarer for solid organ neoplasms to present with hypercalcemia mediated through the production of 1,25-dihydroxyvitamin D3. We report a case of ...

background: patients which have diagnosed with a cancer, have a life time risk for developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. cancer victims could survive longer due to settling treatment modalities, and then would likely develop a new metachronous malignancy. this article aims to report our observed trend of increasing, in p...

conclusions the patients with diffuse pjs may be asymptomatic and without gastrointestinal or extragastrointestinal malignancies. introduction peutz-jeghers syndrome (pjs) is a rare disorder characterized by mucocutaneous perioral pigmentation, gastrointestinal hamartomatous polyposis, and an increased risk of malignancy. families with pjs may show a variable spectrum of manifestations in spite...

Gastrointestinal tuberculosis occurs most often in the ileocecal region, but it can also occur in other locations in the gastrointestinal system. However, few cases with isolated gastrointestinal involvement have been reported. A 27-year-old female presented with abdominal pain, fatigue, weakness, weight loss, and anorexia. A mass was identified in her right lower abdominal quadrant on physical...

We present a rare case of Peutz-Jeghers(P-J) syndrome in a 29-year-old woman who developed adenocarcinoma of the thyroid and polyps in the gastrointestinal tract. Polyps removed from the stomach, colon and ileum showed features typical of hamartomas. Histological examination indicated that the tumor resected from the right lobe of the thyroid was a papillary adenocarcinoma. This appears to be t...

Sister Joseph nodule is a metastatic umbilical lesion secondary to a primary malignancy of any viscera. It can be a presenting symptom (a sign of undiagnosed malignancy) or a symptom or sign of progression or recurrence in a known case. Its incidence is 1%-3% of all intra-abdominal or pelvic malignancies. Here, we present 4 such cases, with Sister Joseph nodule as a finding ofpresentation in a ...