Abstract. The goal of this project is to determine the absorbed dose of radiation to a patient using 99mTc-MAA as a tracer for a lung scan using the MIRD formula accounting only for the radiation dose contributed by the target organ. The radiation dose for other organs to the target organ is considered negligible as the uptake of 99mTc-MAA from other organs is less than 1%. In addition to calcu...

Dosimetry is the process of calculating the effective radioactive dose that is applied to tumors and organs respectively as a patient undergoes a peptide receptor radionuclide therapy. This work presents the novel application software ‘DoSE8’ that was developed from our group and that incorporates all necessary image processing steps (registration and segmentation) and data handling for (partly...

Mucosa-adhesive gels can be used as a useful mean of delivering drugs to or via mucosal membranes, and in particular buccal mucosa. Carbomers are among the best mucosa-adhesive materials known. The aim of this study was to compare the results obtained from the mucosa-adhesive strength of aqueous gels containing Carbomers, either alone or in combination, to the data obtained from assessing the d...

The value of the fundamental quality in radiometry, the watt, is presently realized by electrical substitution in which the temperature produced in a blackened material due to absorption of radiant energy is balanced against that produced by electrical energy whose current and voltage can accurately be measured. A new method to measure optical radiation is being explored by the National Bureau ...

Modern radiation techniques aim on improved 3-dimensional (3D) spatial selectivity of the dose application sparing dose from organs-at-risk (e.g. IMRT with micro-multileaf collimation, γ-knife-, Brachyand heavy-ion therapy). The corresponding 3D-dose distributions exhibit high dose gradients above 4 Gy/mm, which are difficult to be investigated using standard single-point dosimetric detectors ...

PURPOSE To determine whether basic fibroblast growth factor (bFGF) and transforming growth factor-beta 2 (TGF-beta 2) influence the contractile activity and the expression of alpha-smooth muscle actin (alpha-SMA) in bovine lens epithelial cells (LECs). To examine whether modulation of contractile activity by these growth factors depends on changes of alpha-SMA expression. METHODS Bovine LECs ...

Introduction: Polymer gels are modern dosimeters providing three dimensional dose distributions. These dosimeters can be used in brachytherapy in which the tumor dimension is relatively small and the dose gradient is high. In this study, the ability of the MAGICA polymer gel was investigated for assessing the absolute dose values as well as the dose distribution of low dose rate (LDR) Ir-192 wi...

In the quantum regime information can be copied with only a finite fidelity. This fidelity gradually increases to 1 as the system becomes classical. In this Letter we show how this fact can be used to directly measure the amount of radiated power. We demonstrate how these principles can be used to build a practical primary standard.

Radiometry, simulations, and photo-polymerization case studies validate a photo-reactor platform with uniform illumination multiple wavelengths for well plates, in-plane flow reactors, droplets.