melon is an economically important crop and iran is considered as its diversity center. to investigate gene action, heritability and number of effective factors for yield and related traits, six generations, namely: p1, p2, f1, f2, bc1, and bc2 of two crosses of mirpanji × tashkandi and mirpanji × abasali were produced and evaluated in the spring of 2008, applyig a complete block design of thre...

We represent the Brownian model for continuous traits with phylogenetic dependence as a variance components model, allowing for the novel estimation of edge weights for every branch of a tree graph. We show that maximum likelihood estimation carries an inherent bias often shrinking internal edges to zero, which is troublesome because this estimate is intended to compare covariance structures as...

Gene expression profiles show considerable promise for the evaluation of the toxic potential of environmental contaminants. For example, any alterations in the pathways of steroid synthesis or breakdown have the potential to Cause endocrine disruption. Therefore monitoring these pathways can provide information relative to a chemical's ability to impact endocrine function. One approach to monit...

Background: Many techniques have been developed to increase DNA molecules into sperms called sperm mediated gene transfer (SMGT) and one of them is electroporation. Sperm mediated gene transfer is an ideal method for mass gene transfer in organisms with external fertilization. Gene transfer is applied to rainbow trout sperm and the effects of electroporation on sperms and rate of gene uptake by...

The aim of this research was to estimate the influence of environmental factors, such as air temperature and milk production, on reproduction traits of primiparous Polish Holstein-Friesian cows. The following reproduction traits were considered: interval from calving to first insemination, interval from first to last insemination, interval from calving to conception, number of inseminations per...

Variance components were estimated from Targhee data collected from 1978 to 1984 on a total of 1,047 ewe and ram lambs at the U.S. Sheep Experiment Station, Dubois, ID. Lambs were fed for 14 wk with ADG recorded every 2 wk. Lambs were provided ad libitum access to a commercial pelleted feed of barley grain and ground alfalfa. ADG for the entire 14-wk period across all years was 249.3 ± 56.5 g. ...

The ability to place a series of gene constructs at a specific site in the genome opens new possibilities for the experimental examination of gene expression and chromosomal position effects. We report that the FLP- FRT site-specific recombination system of the yeast 2mu plasmid can be used to integrate DNA at a chromosomal FRT target site in Drosophila. The technique we used was to first integ...

Antipsychotic medications are the gold-standard treatment for schizophrenia, and are often prescribed for other mental conditions. However, the efficacy and side-effect profiles of these drugs are heterogeneous, with large interindividual variability. As a result, treatment selection remains a largely trial-and-error process, with many failed treatment regimens endured before finding a tolerabl...