Introduction Sexually transmitted diseases are not only highly prevalent in many populations of the developing world, but exhibit some special features. These include a high rate of complications and sequelae as a result of delayed or inadequate treatment, the important problem of antimicrobial resistance, particularly in Neisseria gonorrhoeae and Haemophilus ducreyi, and a high frequency of ge...

Herpes simplex viruses (HSVs) can cause a variety of infections, including genital herpes. Despite effective antiviral therapy, HSV infections remain a significant worldwide public health problem. Vaccines offer the best hope for controlling spread and limiting HSV disease. This article discusses the pathogenesis and immunobiology of mucocutaneous HSV infections, summarizes the spectrum of dise...

The causative organism of chancroid, Haemophilus ducreyi, is generally considered to be very fastidious and its isolation, maintenance, and detailed study very demanding. In this study a modified medium was developed, which allowed the organism to be isolated more frequently than previously would have been expected. Twenty-two cases of chancroid were confirmed by the isolation of H ducreyi in 1...

The Epstein-Barr virus (EBV) is associated with a broad spectrum of diseases, mainly because of its genomic characteristics, which result in different latency patterns in immune cells and infective mechanisms. The patient described in this report is a previously healthy young man who presented to the emergency department with clinical features consistent with meningitis and genital ulcers, whic...

The association of genital herpetic infections with gonorrhoea and other venereal diseases has been noted since the latter part of the 19th century (Diday and Doyon, 1886). Recently, Beilby, Cameron, Catterall, and Davidson (1968) in England have suggested the possibility that gonorrhoeal infection may trigger recurrences of herpetic cervicitis. To test this hypothesis, the present study was co...

Because genital tuberculosis is frequently asymptomatic, the disease may not manifest itself for years after initial infection. Clinical symptoms usually appear 10 to 15 We report a case of 47 old women with history right breast cancer who was suffering from post menauposicmetrorrhagia, ultrasound revealed thickening endometrium, and biopsy endometrial tuberculosis, Genital uncommon in postmeno...

The reactivity of a non-specific reagin (RPR) test and a specific treponemal (FTA-ABS) test were determined in 21 patients with primary syphilis, 430 patients with proven non-treponemal genital ulcerations and 719 patients with acute urethritis presenting at a clinic for sexually transmitted diseases in southern Africa. Excluding those 21 cases of primary syphilis, 358 of 1149 tests performed (...

Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmission, with an increased risk of infection in women compared to men. Several ch...

214 patients with genital herpes infection proven by culture and a control group of 410 other patients were included in a retrospective study devised to investigate the relationship of circumcision to genital HSV infection in the male. The percentage of patients circumicised in the control group was significantly larger than in the herpes group (P less than 0-01). The was not found to be the ca...

Genital Ulcer Diseases are defined as ulcerative, erosive, pustular or vesicular genital lesion(s), with or without regional lymphadenopathy, caused by a number of sexually transmitted infections (STIs) and non–STI-related conditions (PHAC, 2013). The etiology of GUD varies globally and temporally. For most young, sexually active patients with GUD, etiology is related to an STI. The annual glob...