Abstract Background This study aimed to describe the efficacy of hysteroscopy in management women with persistent gestational trophoblastic disease (PGTD)/GTN reduce need for chemotherapy. Materials and methods prospective, single-arm, clinical trial was recruited an educational referral hospital between September 2018 2019. Totally, 30 participants a history hydatidiform mole that managed by u...

Invasive mole is a rare gestational trophoblastic neoplasia with proliferative trophoblast invading into myometrium or uterine vasculature. Primary management of invasive chemotherapy, but hysterectomy can be performed in selective cases. In this report, we discuss two cases mole, which required surgical intervention the form hysterectomy. Both patients had favorable outcome and are remission.

We read the presented case of retained invasive placenta mimicked gestational choriocarcinoma (GCC)with an enthusiasm [1]. We thought if this is a case of GCC, which sign should be the leading sign. The clinical diagnosis ofGCC is challenging inmost of the cases. The predominant symptom is abnormal vaginal bleeding. Serum human chorionic gonadotropin beta (β-hCG) measurement and doppler ultraso...

Clinical reports of kidney metastases derived from an invasive mole (IM) are rare. The present study presents the case of a 42-year-old woman who exhibited IM and bilateral kidneys metastases in what may be, to the best of our knowledge, the first report of such a case. Following an induced abortion, the patient initially experienced irregular vaginal bleeding and subsequently presented with le...

Treatment of persistent gestational trophoblastic neoplasia (GTN) has been one of the success stories of modern day chemotherapy; however, occasional patients with metastatic disease still die. A potential difficulty in assessing published studies is that patient groups can be selected for treatment differently according to how risk categories are defined. The involvement of a specialist team f...

OBJECTIVE Can polymer-based immunohistochemical staining of p57(kip2) replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? METHODS AND MATERIALS Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and examined by immunohistochemical staining of p57(kip2). RESULTS Four of the 14 c...